Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
3R01AA006092-04S1
Application #
3109321
Study Section
Alcohol Biomedical Research Review Committee (ALCB)
Project Start
1984-09-01
Project End
1990-08-31
Budget Start
1987-09-30
Budget End
1988-08-31
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Roll, F J; Perez, H D; Serhan, C N (1992) Characterization of a novel arachidonic acid-derived neutrophil chemoattractant. Biochem Biophys Res Commun 186:269-76
Roll, F J; Alexander, M A; Cua, D et al. (1991) Metabolism of ethanol by rat hepatocytes results in generation of a lipid chemotactic factor: studies using a cell-free system and role of oxygen-derived free radicals. Arch Biochem Biophys 287:218-24
Hultcrantz, R; Bissell, D M; Roll, F J (1991) Iron mediates production of a neutrophil chemoattractant by rat hepatocytes metabolizing ethanol. J Clin Invest 87:45-9
Neuschwander-Tetri, B A; Roll, F J (1990) Chemotactic activity for human PMN generated during ethanol metabolism by rat hepatocytes: role of glutathione and glutathione peroxidase. Biochem Biophys Res Commun 167:1170-6
Neuschwander-Tetri, B A; Roll, F J (1989) Glutathione measurement by high-performance liquid chromatography separation and fluorometric detection of the glutathione-orthophthalaldehyde adduct. Anal Biochem 179:236-41
Friedman, S L; Roll, F J (1987) Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan. Anal Biochem 161:207-18
Roll, F J; Bissell, D M; Perez, H D (1986) Human hepatocytes metabolizing ethanol generate a non-polar chemotactic factor for human neutrophils. Biochem Biophys Res Commun 137:688-94
Friedman, S L; Roll, F J; Boyles, J et al. (1985) Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci U S A 82:8681-5