Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA006548-09
Application #
2043490
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1994-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Pharmacology
Type
Schools of Medicine
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Savage, Daniel D; Becher, Matthew; de la Torre, Alejandro J et al. (2002) Dose-dependent effects of prenatal ethanol exposure on synaptic plasticity and learning in mature offspring. Alcohol Clin Exp Res 26:1752-8
Weeber, E J; Savage, D D; Sutherland, R J et al. (2001) Fear conditioning-induced alterations of phospholipase C-beta1a protein level and enzyme activity in rat hippocampal formation and medial frontal cortex. Neurobiol Learn Mem 76:151-82
Savage, D D; Galindo, R; Queen, S A et al. (2001) Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices. Neurochem Int 38:255-67
Costa, E T; Olivera, D S; Meyer, D A et al. (2000) Fetal alcohol exposure alters neurosteroid modulation of hippocampal N-methyl-D-aspartate receptors. J Biol Chem 275:38268-74
Costa, E T; Savage, D D; Valenzuela, C F (2000) A review of the effects of prenatal or early postnatal ethanol exposure on brain ligand-gated ion channels. Alcohol Clin Exp Res 24:706-15
Savage, D D; Cruz, L L; Duran, L M et al. (1998) Prenatal ethanol exposure diminishes activity-dependent potentiation of amino acid neurotransmitter release in adult rat offspring. Alcohol Clin Exp Res 22:1771-7
Perrone-Bizzozero, N I; Isaacson, T V; Keidan, G M et al. (1998) Prenatal ethanol exposure decreases GAP-43 phosphorylation and protein kinase C activity in the hippocampus of adult rat offspring. J Neurochem 71:2104-11
Allan, A M; Wu, H; Paxton, L L et al. (1998) Prenatal ethanol exposure alters the modulation of the gamma-aminobutyric acidA1 receptor-gated chloride ion channel in adult rat offspring. J Pharmacol Exp Ther 284:250-7
Allan, A M; Weeber, E J; Savage, D D et al. (1997) Effects of prenatal ethanol exposure on phospholipase C-beta 1 and phospholipase A2 in hippocampus and medial frontal cortex of adult rat offspring. Alcohol Clin Exp Res 21:1534-41
Carpenter, S P; Savage, D D; Schultz, E D et al. (1997) Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver. J Pharmacol Exp Ther 282:1028-36

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