Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA009227-04
Application #
2045451
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1992-04-01
Project End
1996-11-30
Budget Start
1995-04-01
Budget End
1996-11-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Larkin, J M; Woo, B; Balan, V et al. (2000) Rab3D, a small GTP-binding protein implicated in regulated secretion, is associated with the transcytotic pathway in rat hepatocytes. Hepatology 32:348-56
McNiven, M A; Marlowe, K J (1999) Contributions of molecular motor enzymes to vesicle-based protein transport in gastrointestinal epithelial cells. Gastroenterology 116:438-51
Chen, X M; Levine, S A; Tietz, P et al. (1998) Cryptosporidium parvum is cytopathic for cultured human biliary epithelia via an apoptotic mechanism. Hepatology 28:906-13
Yoon, Y; Torok, N; Krueger, E et al. (1998) Ethanol-induced alterations of the microtubule cytoskeleton in hepatocytes. Am J Physiol 274:G757-66
Urrutia, R; Henley, J R; Cook, T et al. (1997) The dynamins: redundant or distinct functions for an expanding family of related GTPases? Proc Natl Acad Sci U S A 94:377-84
Torok, N; Marks, D; Hsiao, K et al. (1997) Vesicle movement in rat hepatocytes is reduced by ethanol exposure: alterations in microtubule-based motor enzymes. Gastroenterology 113:1938-48
Torok, N; Urrutia, R; Nakamura, T et al. (1996) Upregulation of molecular motor-encoding genes during hepatocyte growth factor- and epidermal growth factor-induced cell motility. J Cell Physiol 167:422-33
Larkin, J M; Oswald, B; McNiven, M A (1996) Ethanol-induced retention of nascent proteins in rat hepatocytes is accompanied by altered distribution of the small GTP-binding protein rab2. J Clin Invest 98:2146-57
Marks, D L; LaRusso, N F; McNiven, M A (1995) Isolation of the microtubule-vesicle motor kinesin from rat liver: selective inhibition by cholestatic bile acids. Gastroenterology 108:824-33
Torre, E; McNiven, M A; Urrutia, R (1994) Dynamin 1 antisense oligonucleotide treatment prevents neurite formation in cultured hippocampal neurons. J Biol Chem 269:32411-7

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