Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA009460-04
Application #
2045679
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1998-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029
Perez, M J; Cederbaum, A I (2001) Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity. Free Radic Biol Med 30:734-46
Clancy, R; Cederbaum, A I; Stoyanovsky, D A (2001) Preparation and properties of S-nitroso-L-cysteine ethyl ester, an intracellular nitrosating agent. J Med Chem 44:2035-8
Novakov, C P; Feierman, D; Cederbaum, A I et al. (2001) An ESR and HPLC-EC assay for the detection of alkyl radicals. Chem Res Toxicol 14:1239-46
Caro, A A; Cederbaum, A I; Stoyanovsky, D A (2001) Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems. Nitric Oxide 5:413-24
Sakurai, K; Stoyanovsky, D A; Fujimoto, Y et al. (2000) Mitochondrial permeability transition induced by 1-hydroxyethyl radical. Free Radic Biol Med 28:273-80
Puntarulo, S; Stoyanovsky, D A; Cederbaum, A I (1999) Interaction of 1-hydroxyethyl radical with antioxidant enzymes. Arch Biochem Biophys 372:355-9
Stoyanovsky, D A; Cederbaum, A I (1999) Metabolism of carbon tetrachloride to trichloromethyl radical: An ESR and HPLC-EC study. Chem Res Toxicol 12:730-6
Stoyanovsky, D A; Melnikov, Z; Cederbaum, A I (1999) ESR and HPLC-EC analysis of the interaction of hydroxyl radical with DMSO: rapid reduction and quantification of POBN and PBN nitroxides. Anal Chem 71:715-21
Puntarulo, S; Cederbaum, A I (1998) Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes. Free Radic Biol Med 24:1324-30
Stoyanovsky, D A; Cederbaum, A I (1998) ESR and HPLC-EC analysis of ethanol oxidation to 1-hydroxyethyl radical: rapid reduction and quantification of POBN and PBN nitroxides. Free Radic Biol Med 25:536-45

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