Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA010114-03
Application #
2046600
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Patel, Dhyanesh; Rathinam, Marylatha; Jarvis, Courtney et al. (2018) Role for Cystathionine ? Lyase (CSE) in an Ethanol (E)-Induced Lesion in Fetal Brain GSH Homeostasis. Int J Mol Sci 19:
Patel, Dhyanesh; Mahimainathan, Lenin; Narasimhan, Madhusudhanan et al. (2017) Ethanol (E) Impairs Fetal Brain GSH Homeostasis by Inhibiting Excitatory Amino-Acid Carrier 1 (EAAC1)-Mediated Cysteine Transport. Int J Mol Sci 18:
Riar, Amanjot Kaur; Narasimhan, Madhusudhanan; Rathinam, Mary Latha et al. (2016) Ethanol induces cytostasis of cortical basal progenitors. J Biomed Sci 23:6
Riar, Amanjot Kaur; Narasimhan, Madhusudhanan; Rathinam, Mary Latha et al. (2014) Ethanol-induced transcriptional activation of programmed cell death 4 (Pdcd4) is mediated by GSK-3? signaling in rat cortical neuroblasts. PLoS One 9:e98080
Narasimhan, Madhusudhanan; Riar, Amanjot Kaur; Rathinam, Mary Latha et al. (2014) Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity. Toxicol Lett 228:179-91
Narasimhan, Madhusudhanan; Rathinam, Marylatha; Riar, Amanjot et al. (2013) Programmed cell death 4 (PDCD4): a novel player in ethanol-mediated suppression of protein translation in primary cortical neurons and developing cerebral cortex. Alcohol Clin Exp Res 37:96-109
Fowler, Anna-Kate; Hewetson, Aveline; Agrawal, Rajiv G et al. (2012) Alcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain. J Biol Chem 287:43533-42
Narasimhan, Madhusudhanan; Rathinam, Marylatha; Patel, Dhyanesh et al. (2012) Astrocytes Prevent Ethanol Induced Apoptosis of Nrf2 Depleted Neurons by Maintaining GSH Homeostasis. Open J Apoptosis 1:
Kruman, Inna I; Henderson, George I; Bergeson, Susan E (2012) DNA damage and neurotoxicity of chronic alcohol abuse. Exp Biol Med (Maywood) 237:740-7
Narasimhan, Madhusudhanan; Patel, Dhyanesh; Vedpathak, Dhanashree et al. (2012) Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells. PLoS One 7:e51111

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