Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA010762-01
Application #
2047413
Study Section
Special Emphasis Panel (SRCA (61))
Project Start
1996-03-01
Project End
2001-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
McClain, Craig; Vatsalya, Vatsalya; Cave, Matthew (2017) Role of Zinc in the Development/Progression of Alcoholic Liver Disease. Curr Treat Options Gastroenterol 15:285-295
Zhao, Cuiqing; Liu, Yanlong; Xiao, Jian et al. (2015) FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice. J Lipid Res 56:1481-91
Smart, Laura; Gobejishvili, Leila; Crittenden, Neil et al. (2013) Alcoholic Hepatitis: Steroids vs. Pentoxifylline. Curr Hepat Rep 12:59-65
Jackson, Sara L; Cook, Andrea J; Miglioretti, Diana L et al. (2012) Are radiologists' goals for mammography accuracy consistent with published recommendations? Acad Radiol 19:289-95
Kirpich, Irina A; Feng, Wenke; Wang, Yuhua et al. (2012) The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease. Alcohol Clin Exp Res 36:835-46
Gobejishvili, Leila; Avila, Diana V; Barker, David F et al. (2011) S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway. J Pharmacol Exp Ther 337:433-43
Heilman, Jacqueline M; Burke, Tom J; McClain, Craig J et al. (2011) Transactivation of gene expression by NF-?B is dependent on thioredoxin reductase activity. Free Radic Biol Med 51:1533-42
Zhao, Yantao; Zhong, Wei; Sun, Xiuhua et al. (2011) Zinc deprivation mediates alcohol-induced hepatocyte IL-8 analog expression in rodents via an epigenetic mechanism. Am J Pathol 179:693-702
Ghare, Smita; Patil, Madhuvanti; Hote, Prachi et al. (2011) Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression. Alcohol Clin Exp Res 35:1435-44
Beier, Juliane I; McClain, Craig J (2010) Mechanisms and cell signaling in alcoholic liver disease. Biol Chem 391:1249-64

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