Prior to the disappointing findings of PROJECT MATCH, patient-treatment matching was viewed as a promising paradigm for increasing alcohol treatment effectiveness. The paucity of findings to support matching treatment modality to patient attribute in MATCH has led researchers to largely abandon this paradigm. However, further study has used observer ratings of therapist interventions from one MATCH aftercare site to successfully support two of three therapist behavior by patient attribute matching hypotheses derived from Beutler and Clarkin's Systematic Treatment Selection model. Specifically, (1) the emotion focus of therapy in response to patient distress before treatment and (2) therapist directiveness in response to patient trait reactance significantly predicted drinking frequency during the year after treatment. The first objective of this proposed continuation is to replicate these findings in a sample of patients randomly selected from an additional MATCH aftercare site (N=127). Additionally, the project will determine the generalizability of these matching effects to an outpatient population by testing for them among a sample of randomly selected patients from MATCH outpatient sites (N=127). The second objective is to test the theoretical underpinnings of these matching effects. It is hypothesized that patient emotional arousal in treatment mediates the relationship between therapy emotion focus and drinking. It is also hypothesized that in-session patient collaboration mediates the relationship between therapist directiveness and drinking. ? Causal chain analysis will be conducted using Baron and Kenny's method to identify mediator variables. The third objective of the project is to test the predictive validity of an a priori multi-dimensional typology for matching therapist interventions to patient attributes. Linear regression analysis will be used to test for differences in post-treatment drinking outcomes among patients who received a matched, partially matched, or mismatched therapy profile. For all three objectives the outcome variables will be frequency of drinking and frequency of heavy drinking during the year after treatment. If positive, the results of this study will: (1) re-establish patient-treatment matching as a valuable paradigm for enhancing patient drinking outcomes, (2) contribute to theory and methodology for studying alcohol treatment effectiveness, and (3) provide clinicians with practical techniques to significantly improve their patients' outcomes. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
3R01AA012155-04A1S1
Application #
7078159
Study Section
Health Services Research Review Subcommittee (AA)
Program Officer
Mattson, Margaret
Project Start
2000-08-01
Project End
2008-07-31
Budget Start
2005-07-01
Budget End
2005-07-31
Support Year
4
Fiscal Year
2005
Total Cost
$81,387
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Karno, Mitchell P; Longabaugh, Richard; Herbeck, Diane (2010) What explains the relationship between the therapist structure × patient reactance interaction and drinking outcome? An examination of potential mediators. Psychol Addict Behav 24:600-7
Karno, Mitchell P; Longabaugh, Richard; Herbeck, Diane (2009) Patient reactance as a moderator of the effect of therapist structure on posttreatment alcohol use. J Stud Alcohol Drugs 70:929-36
Longabaugh, Richard (2007) The search for mechanisms of change in behavioral treatments for alcohol use disorders: a commentary. Alcohol Clin Exp Res 31:21s-32s
Karno, Mitchell P (2007) A case study of mediators of treatment effectiveness. Alcohol Clin Exp Res 31:33s-39s
Karno, Mitchell P; Longabaugh, Richard (2007) Does matching matter? Examining matches and mismatches between patient attributes and therapy techniques in alcoholism treatment. Addiction 102:587-96
Karno, Mitchell P; Longabaugh, Richard (2005) An examination of how therapist directiveness interacts with patient anger and reactance to predict alcohol use. J Stud Alcohol 66:825-32
Karno, Mitchell P; Longabaugh, Richard (2005) Less directiveness by therapists improves drinking outcomes of reactant clients in alcoholism treatment. J Consult Clin Psychol 73:262-7
Longabaugh, Richard; Donovan, Dennis M; Karno, Mitchell P et al. (2005) Active ingredients: how and why evidence-based alcohol behavioral treatment interventions work. Alcohol Clin Exp Res 29:235-47
Karno, Mitchell P; Longabaugh, Richard (2004) What do we know? Process analysis and the search for a better understanding of Project MATCH's anger-by-treatment matching effect. J Stud Alcohol 65:501-12
Karno, Mitchell P; Longabaugh, Richard (2003) Patient depressive symptoms and therapist focus on emotional material: a new look at Project MATCH. J Stud Alcohol 64:607-15

Showing the most recent 10 out of 11 publications