Alcohol and drug abusing and dependent delinquents represent a greatly under served population that is at high risk of presenting significant deleterious long-term outcomes and costs (emotional, physical, financial) for themselves, their families, communities, and society. In designing treatment services for this population, it is critical to address the empirically determined contributors to alcohol and drug abuse in adolescents. Specifically, extensive and sophisticated research findings support the view that adolescent alcohol and drug use and abuse are multi-determined, linked directly or indirectly with cognitive/emotional characteristics of youths and key aspects of the family, peer, school, and neighborhood systems in which youths are embedded. Short-term and long-term outcomes from eight randomized trials of multisystemic therapy demonstrate that MST holds considerable promise in the treatment of serious clinical problems in adolescents and their families. Recognition of such promise is becoming widespread among leading academics and policy makers in the fields of substance abuse,juvenile justice, and mental health. Such promise is due largely to the capacity of MST to provide individualized and comprehensive services that overcome barriers to service delivery and directly address the multiple factors linked with antisocial behavior in the natural environments of youths and families. With regard to the treatment of alcohol abuse and dependence, four studies of MST have demonstrated at least short-term reductions in alcohol and drug use with adolescents presenting serious clinical problems. In light of these encouraging but not definitive results, this application proposes a rigorous study of the effectiveness of MST (plus an enhancement that integrates key components of the Community Reinforcement Approach under conditions of high treatment fidelity. Specifically, in a 2 (treatment condition: MST vs. current community services [CS]) x 4 (time: pretreatment, posttreatment, 6-month follow-up, 12-month follow-up) design, 144 juvenile offenders who meet DSM-IV criteria for alcohol abuse or dependence will be randomly assigned to MST versus CS treatment conditions. A comprehensive multimethod, multisource evaluation will address the following aims:
Aim 1. To evaluate MST treatment effects on adolescent alcohol and drug use, criminal activity, and mental health functioning; as well as on family relations, peer relations, and school attendance.
Aim 2. To track substance abuse and mental health service utilization and their associated costs across the treatment conditions to the 12-month follow-up.
Aim 3. To test hypotheses about the mediators and moderators of MST treatment effects.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA012202-02
Application #
6168490
Study Section
Special Emphasis Panel (ZAA1-BB (01))
Program Officer
Lowman, Cherry
Project Start
1999-09-02
Project End
2004-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
2
Fiscal Year
2000
Total Cost
$820,900
Indirect Cost
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Gillespie, Marie L; Huey Jr, Stanley J; Cunningham, Phillippe B (2017) Predictive validity of an observer-rated adherence protocol for multisystemic therapy with juvenile drug offenders. J Subst Abuse Treat 76:1-10
Li, Chong; Xue, ChunLai; Liu, Zhi et al. (2016) High-responsivity vertical-illumination Si/Ge uni-traveling-carrier photodiodes based on silicon-on-insulator substrate. Sci Rep 6:27743
Wang, Jing; Qi, Minghao; Xuan, Yi et al. (2014) Proposal for fabrication-tolerant SOI polarization splitter-rotator based on cascaded MMI couplers and an assisted bi-level taper. Opt Express 22:27869-79
Wang, Jing; Niu, Ben; Sheng, Zhen et al. (2014) Novel ultra-broadband polarization splitter-rotator based on mode-evolution tapers and a mode-sorting asymmetric Y-junction. Opt Express 22:13565-71
Halliday-Boykins, Colleen A; Schaeffer, Cindy M; Henggeler, Scott W et al. (2010) Predicting nonresponse to juvenile drug court interventions. J Subst Abuse Treat 39:318-28
McCollister, Kathryn E; French, Michael T; Sheidow, Ashli J et al. (2009) Estimating the differential costs of criminal activity for juvenile drug court participants: challenges and recommendations. J Behav Health Serv Res 36:111-26
Foster, Sharon L; Cunningham, Phillippe B; Warner, Sarah E et al. (2009) Therapist behavior as a predictor of black and white caregiver responsiveness in multisystemic therapy. J Fam Psychol 23:626-35
Chapman, Jason E; Sheidow, Ashli J; Henggeler, Scott W et al. (2008) Developing a Measure of Therapist Adherence to Contingency Management: An Application of the Many-Facet Rasch Model. J Child Adolesc Subst Abuse 17:47-68
Schoenwald, Sonja K; Letourneau, Elizabeth J; Halliday-Boykins, Colleen (2005) Predicting therapist adherence to a transported family-based treatment for youth. J Clin Child Adolesc Psychol 34:658-70
Randall, Jeff; Cunningham, Phillippe B (2003) Multisystemic therapy: a treatment for violent substance-abusing and substance-dependent juvenile offenders. Addict Behav 28:1731-9