Among HIV-infected individuals, drinking can interfere with antiretroviral treatment and with treatment of HCV among those co-infected. Further, end-stage liver disease is now a common cause of mortality in HIV patients, so managing unsafe drinking in this group is crucial to their care. The goal of this study (responding to NIAAA PA-02-039) is to test the efficacy of a drinking-reduction intervention in HIV primary care patients. The intervention has two components. One is a brief motivational interview (Ml), an evidence-based intervention often used in primary care. The other, HealthCall, was created to enhance Ml effects. HealthCall involves daily 1-3 minute calls to a toll-free telephone interactive voice response system. User-friendly questions in English or Spanish ask branching questions about drinking and other health concerns in the prior 24 hours. Patients input responses by voice or telephone touchpad. Monthly, they receive feedback: a bar graph generated from the HealthCall database displaying their daily drinking in the prior 30 days, discussed with their Ml counselor. Pilot work in a large, low-SES HIV primary care clinic demonstrated feasibility and suggested efficacy; this clinic and another will be the sites of the study. Ml and MI+HealthCall will be studied among 348 patients randomly assigned to three groups. Group 1, controls, will view a 30- minute DVD on self-care and latest developments in HIV. Group 2 will receive a 30-minute Ml adapted for HIV patients. Group 3 will receive the 30-minute Ml plus HealthCall. All groups will receive NIAAA pamphlets. Follow-up will be at 3, 6 and 12 months. Primary outcomes are drinking quantity and frequency. Mediators of intervention effects on drinking (motivation and self-efficacy)and secondary health outcomes will be explored. Analysis will include marginal linear models for repeated measures using GEE estimation. Successful results would contribute to effective, sustainable drinking-reduction interventions in HIV-infected individuals to promote their long-term health, and to adaptation of the innovative model for other important outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA014323-03
Application #
7281695
Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Bryant, Kendall
Project Start
2005-09-30
Project End
2010-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
3
Fiscal Year
2007
Total Cost
$536,406
Indirect Cost
Name
New York State Psychiatric Institute
Department
Type
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Algur, Yasemin; Elliott, Jennifer C; Aharonovich, Efrat et al. (2018) A Cross-Sectional Study of Depressive Symptoms and Risky Alcohol Use Behaviors Among HIV Primary Care Patients in New York City. AIDS Behav 22:1423-1429
Gause, Nicole K; Elliott, Jennifer C; Delker, Erin et al. (2018) Association between change in self-efficacy to resist drinking and drinking behaviors among an HIV-infected sample: Results from a large randomized controlled trial. J Health Psychol 23:829-839
Aharonovich, Efrat; Sarvet, Aaron; Stohl, Malki et al. (2017) Reducing non-injection drug use in HIV primary care: A randomized trial of brief motivational interviewing, with and without HealthCall, a technology-based enhancement. J Subst Abuse Treat 74:71-79
Elliott, Jennifer C; Delker, Erin; Wall, Melanie M et al. (2016) Neighborhood-Level Drinking Norms and Alcohol Intervention Outcomes in HIV Patients Who Are Heavy Drinkers. Alcohol Clin Exp Res 40:2240-2246
Elliott, Jennifer C; Stohl, Malka; Aharonovich, Efrat et al. (2016) Reasons for drinking as predictors of alcohol involvement one year later among HIV-infected individuals with and without hepatitis C. Ann Med 48:634-640
Elliott, Jennifer C; Delker, Erin; Wall, Melanie M et al. (2016) The Importance of Context: Neighborhood Drinking Norms and Heavy Drinking Among HIV Patients. J Acquir Immune Defic Syndr 72:e55-7
Elliott, Jennifer C; Aharonovich, Efrat; Hasin, Deborah S (2015) Post-treatment drinking among HIV patients: Relationship to pre-treatment marijuana and cocaine use. Drug Alcohol Depend 151:115-20
Aharonovich, Efrat; Stohl, Malka; Ellis, James et al. (2014) Commitment strength, alcohol dependence and HealthCall participation: effects on drinking reduction in HIV patients. Drug Alcohol Depend 135:112-8
Elliott, Jennifer C; Aharonovich, Efrat; Hasin, Deborah S (2014) Reasons for limiting drinking in an HIV primary care sample. Alcohol Clin Exp Res 38:1720-7
Hasin, Deborah S; Aharonovich, Efrat; Greenstein, Eliana (2014) HealthCall for the smartphone: technology enhancement of brief intervention in HIV alcohol dependent patients. Addict Sci Clin Pract 9:5

Showing the most recent 10 out of 14 publications