Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA024405-01
Application #
8993659
Study Section
Special Emphasis Panel (ZAA1-GG (50))
Program Officer
Wang, Joe
Project Start
2015-03-10
Project End
2020-02-28
Budget Start
2015-03-10
Budget End
2016-02-29
Support Year
1
Fiscal Year
2015
Total Cost
$300,000
Indirect Cost
$100,000

  Institution

Name
University of Louisville
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40202

  Publications

Avila, Diana V; Myers, Scott A; Zhang, JingWen et al. (2017) Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation. Neuropharmacology 125:376-385
Barve, Shirish; Chen, Shao-Yu; Kirpich, Irina et al. (2017) Development, Prevention, and Treatment of Alcohol-Induced Organ Injury: The Role of Nutrition. Alcohol Res 38:289-302
McClain, Craig; Barve, Shirish (2017) A tale of two institutions. J Hepatol 66:682-684
Chen, Wei-Yang; Wang, Min; Zhang, Jingwen et al. (2017) Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability. Am J Pathol 187:2686-2697
Vatsalya, Vatsalya; Barve, Shirish S; McClain, Craig J et al. (2016) Elevated Linoleic Acid (A Pro-Inflammatory PUFA) and Liver Injury in a Treatment Naive HIV-HCV Co-Infected Alcohol Dependent Patient. J Biosci Med (Irvine) 4:23-27
Ghare, Smita S; Donde, Hridgandh; Chen, Wei-Yang et al. (2016) Acrolein enhances epigenetic modifications, FasL expression and hepatocyte toxicity induced by anti-HIV drug Zidovudine. Toxicol In Vitro 35:66-76
Vatsalya, Vatsalya; Pandey, Akash; Schwandt, Melanie L et al. (2016) Safety Assessment of Liver Injury with Quetiapine Fumarate XR Management in Very Heavy Drinking Alcohol-Dependent Patients. Clin Drug Investig 36:935-944
Vatsalya, Vatsalya; Avila, Diana; Frimodig, Jane C et al. (2016) Liver Injury Assessment by Vetscan VS2 Analyzer and Most Frequently Used ALT/GTP Reagent. Gastroenterol Hepatol (Bartlesville) 4:
Kirpich, Irina A; Petrosino, Joseph; Ajami, Nadim et al. (2016) Saturated and Unsaturated Dietary Fats Differentially Modulate Ethanol-Induced Changes in Gut Microbiome and Metabolome in a Mouse Model of Alcoholic Liver Disease. Am J Pathol 186:765-76
Avila, Diana V; Barker, David F; Zhang, JingWen et al. (2016) Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis. J Pathol 240:96-107

Showing the most recent 10 out of 12 publications