Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG005940-02S1
Application #
3116662
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1986-08-01
Project End
1990-07-31
Budget Start
1988-03-10
Budget End
1988-07-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Pharmacy
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Schwartz, J B (1996) Calcium antagonists in the elderly. A risk-benefit analysis. Drugs Aging 9:24-36
Craft, N; Schwartz, J B (1995) Effects of age on intrinsic heart rate, heart rate variability, and AV conduction in healthy humans. Am J Physiol 268:H1441-52
Harris, R Z; Benet, L Z; Schwartz, J B (1995) Gender effects in pharmacokinetics and pharmacodynamics. Drugs 50:222-39
Schwartz, J B; Shen, C; Garcia, J et al. (1995) Influence of autonomic blockade and aging on AV conduction and responses to verapamil in the beagle. J Gerontol A Biol Sci Med Sci 50:M83-90
Schwartz, J B; Capili, H; Daugherty, J (1994) Aging of women alters S-verapamil pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 55:509-17
Kusumoto, F M; Lurie, K G; Dutton, J et al. (1994) Effects of aging on AV nodal and ventricular beta-adrenergic receptors in the Fischer 344 rat. Am J Physiol 266:H1408-15
Schwartz, J B; Capili, H; Wainer, I W (1994) Verapamil stereoisomers during racemic verapamil administration: effects of aging and comparisons to administration of individual stereoisomers. Clin Pharmacol Ther 56:368-76
Schwartz, J B; Caputo, G; Abbott, J (1993) Early experience with dobutamine stress testing and cardiac cine-tomographic imaging in the elderly: antianginal effects of nifedipine-GITS. J Am Geriatr Soc 41:967-74
Schwartz, J B; Troconiz, I F; Verotta, D et al. (1993) Aging effects on stereoselective pharmacokinetics and pharmacodynamics of verapamil. J Pharmacol Exp Ther 265:690-8
Schrader, R; Brooks, M; Echt, D S (1992) Effects of verapamil and Bay K 8644 on defibrillation energy requirements in dogs. J Cardiovasc Pharmacol 19:839-50

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