The objective of the proposed work is to develop a safe balance """"""""stress test"""""""" that can be used as a predictor of relative falling liability in elderly individuals. Such a test could then be used to identify """"""""high-risk"""""""" individuals and to study possible causal and preventative factors. The balance stress test is based on an hypothesis that the posture control system acts to maximize the """"""""stability margin"""""""", the distance between the center-of-pressure on the feet (COP) and the limits of the base-of-support (BOS). If this hypothesis is true, then it may be possible to quantify the relative falling liability of an indivudal in terms of the stability margin of the response to a transient perturbation (simulating a trip, slip or misstep). For safety reasons, the transient response cannot be measured directly. Instead, a safe small-amplitude random or pseudo random perturbation is used to identify an input-output model of the posture control system, which is then used to predict the transient response and stability margin. The proposed work will test the ability of the balance stress test to predict relative falling liability in a population of elderly subjects. The predicted falling liability will be compared with actual falling behaviour moitored prospectively over a period of one year through self-reporting, observation by clinical staff and interviews. To allow observation of falls, the subjects will be seleced from a population of institutionalized, yet ambulatory elderly. The test predictions and actual oberved incidence of falling will be compared, both with and without allowance for errors in the fall-reporting (i.e. non-falling fallers and falling non-fallers). In addition, the result will be compared to those obtained using conventional spontaneous sway mesures as the predictor falling liability, and to results obtained when consideration is given to other risk factors (physiological, activity/lifestyle, environmental and gait-related).

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG006357-03
Application #
3117361
Study Section
(SSS)
Project Start
1986-09-29
Project End
1990-08-31
Budget Start
1988-09-01
Budget End
1990-08-31
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Toronto
Department
Type
DUNS #
259999779
City
Toronto
State
ON
Country
Canada
Zip Code
M5 1S8
Maki, B E (1997) Gait changes in older adults: predictors of falls or indicators of fear. J Am Geriatr Soc 45:313-20
Maki, B E; McIlroy, W E (1996) Postural control in the older adult. Clin Geriatr Med 12:635-58
Liu, B A; Topper, A K; Reeves, R A et al. (1995) Falls among older people: relationship to medication use and orthostatic hypotension. J Am Geriatr Soc 43:1141-5
Maki, B E; Holliday, P J; Topper, A K (1994) A prospective study of postural balance and risk of falling in an ambulatory and independent elderly population. J Gerontol 49:M72-84
Topper, A K; Maki, B E; Holliday, P J (1993) Are activity-based assessments of balance and gait in the elderly predictive of risk of falling and/or type of fall? J Am Geriatr Soc 41:479-87
Maki, B E (1993) Biomechanical approach to quantifying anticipatory postural adjustments in the elderly. Med Biol Eng Comput 31:355-62
Maki, B E; Holliday, P J; Topper, A K (1991) Fear of falling and postural performance in the elderly. J Gerontol 46:M123-31