Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG007700-09
Application #
2049861
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1988-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Wang, H Y; Bashore, T R; Tran, Z V et al. (2000) Age-related decreases in lymphocyte protein kinase C activity and translocation are reduced by aerobic fitness. J Gerontol A Biol Sci Med Sci 55:B545-51
Zhen, X; Uryu, K; Cai, G et al. (1999) Age-associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats. J Gerontol A Biol Sci Med Sci 54:B539-48
Bhamre, S; Wang, H Y; Friedman, E (1998) Serotonin-mediated palmitoylation and depalmitoylation of G alpha proteins in rat brain cortical membranes. J Pharmacol Exp Ther 286:1482-9
Gurdal, H; Friedman, E; Johnson, M D et al. (1998) Decrease in apparent alpha1-adrenoceptor-G protein coupling during maturation in rat aorta. J Gerontol A Biol Sci Med Sci 53:B268-73
Gurdal, H; Seasholtz, T M; Wang, H Y et al. (1997) Role of G alpha q or G alpha o proteins in alpha 1-adrenoceptor subtype-mediated responses in Fischer 344 rat aorta. Mol Pharmacol 52:1064-70
Cai, G; Wang, H Y; Gao, E et al. (1997) Reduced adenosine A1 receptor and G alpha protein coupling in rat ventricular myocardium during aging. Circ Res 81:1065-71
Tilakaratne, N; Friedman, E (1996) Genomic responses to 5-HT1A or 5-HT2A/2C receptor activation is differentially regulated in four regions of rat brain. Eur J Pharmacol 307:211-7
Gurdal, H; Tilakaratne, N; Brown, R D et al. (1995) The expression of alpha 1 adrenoceptor subtypes changes with age in the rat aorta. J Pharmacol Exp Ther 275:1656-62
Undie, A S; Wang, H Y; Friedman, E (1995) Decreased phospholipase C-beta immunoreactivity, phosphoinositide metabolism, and protein kinase C activation in senescent F-344 rat brain. Neurobiol Aging 16:19-28
Gurdal, H; Friedman, E; Johnson, M D (1995) Effects of dietary restriction on the change in aortic alpha 1-adrenoceptor mediated responses during aging in Fischer 344 rats. J Gerontol A Biol Sci Med Sci 50:B67-71

Showing the most recent 10 out of 26 publications