Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
2R01AG008226-06A2
Application #
2050121
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1989-06-01
Project End
2001-06-30
Budget Start
1996-07-17
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Chakrabarti, Subrata; Blair, Price; Wu, Cindy et al. (2007) Redox state of dipyridamole is a critical determinant for its beneficial antioxidant and antiinflammatory effects. J Cardiovasc Pharmacol 50:449-57
Freedman, Jane E (2005) Molecular regulation of platelet-dependent thrombosis. Circulation 112:2725-34
Chakrabarti, Subrata; Vitseva, Olga; Iyu, David et al. (2005) The effect of dipyridamole on vascular cell-derived reactive oxygen species. J Pharmacol Exp Ther 315:494-500
Iafrati, Mark D; Vitseva, Olga; Tanriverdi, Kahraman et al. (2005) Compensatory mechanisms influence hemostasis in setting of eNOS deficiency. Am J Physiol Heart Circ Physiol 288:H1627-32
Vitseva, Olga; Flockhart, David A; Jin, Yan et al. (2005) The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates. J Pharmacol Exp Ther 312:1144-50
Vitseva, Olga; Varghese, Sonia; Chakrabarti, Subrata et al. (2005) Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates. J Cardiovasc Pharmacol 46:445-51
Albers, Anne R; Varghese, Sonia; Vitseva, Olga et al. (2004) The antiinflammatory effects of purple grape juice consumption in subjects with stable coronary artery disease. Arterioscler Thromb Vasc Biol 24:e179-80
Freedman, Jane E (2003) CD40-CD40L and platelet function: beyond hemostasis. Circ Res 92:944-6
Freedman, J E; Loscalzo, J (2003) Nitric oxide and its relationship to thrombotic disorders. J Thromb Haemost 1:1183-8
Abernethy, Darrell R; Pezzullo, John; Mascelli, Mary A et al. (2002) Pharmacodynamics of abciximab during angioplasty: comparison to healthy subjects. Clin Pharmacol Ther 71:186-95

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