Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
2R01AG008438-05A2
Application #
2001304
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1996-09-30
Project End
1997-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Jaszewski, R; Ehrinpreis, M N; Majumdar, A P (1999) Aging and cancer of the stomach and colon. Front Biosci 4:D322-8
Majumdar, A P; Goldenring, J R (1998) Localization and significance of pp55, a gastric mucosal membrane protein with tyrosine kinase activity. Am J Physiol 274:G863-70
Malecka-Panas, E; Fligiel, S E; Jaszewski, R et al. (1997) Differential responsiveness of proximal and distal colonic mucosa to gastrin. Peptides 18:559-65
Tureaud, J; Sarkar, F H; Fligiel, S E et al. (1997) Increased expression of EGFR in gastric mucosa of aged rats. Am J Physiol 273:G389-98
Majumdar, A P; Jaszewski, R; Dubick, M A (1997) Effect of aging on the gastrointestinal tract and the pancreas. Proc Soc Exp Biol Med 215:134-44
Majumdar, A P; Fligiel, S E; Jaszewski, R (1997) Gastric mucosal injury and repair: effect of aging. Histol Histopathol 12:491-501
Malecka-Panas, E; Fligiel, S E; Relan, N K et al. (1996) Azoxymethane enhances ligand-induced activation of EGF receptor tyrosine kinase in the colonic mucosa of rats. Carcinogenesis 17:233-7
Majumdar, A P; Fligiel, S E; Jaszewski, R et al. (1996) Inhibition of gastric mucosal regeneration by tyrphostin: evaluation of the role of epidermal growth factor receptor tyrosine kinase. J Lab Clin Med 128:173-80
Moshier, J A; Malecka-Panas, E; Geng, H et al. (1995) Ornithine decarboxylase transformation of NIH/3T3 cells is mediated by altered epidermal growth factor receptor activity. Cancer Res 55:5358-65
Relan, N K; Saeed, A; Ponduri, K et al. (1995) Identification and evaluation of the role of endogenous tyrosine kinases in azoxymethane induction of proliferative processes in the colonic mucosa of rats. Biochim Biophys Acta 1244:368-76

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