The purpose of the proposed study is to address the distinct need in epidemiologic studies for noninvasive, simple, but reliable methods for estimating body composition and patterning in elderly persons 65+ years of age. The term """"""""body composition"""""""" refers to total body fat (TBF), the percent of weight that is fat (%BF), fat-free mass (FFM), total body water (TBW), and extra-cellular fluid (ECF). """"""""Fat patterning"""""""" (FP) refers to the anatomical distribution of subcutaneous adipose tissue. Significant changes in body composition and fat patterning that have important health related effects occur with aging and knowledge of these changes is important for diagnoses, prognoses, and treatment of the elderly. There are few data, however, for body composition and fat patterning in the elderly because traditional methods have been difficult to apply for technical, conceptual or cost reasons. The proposed study will focus on the refinement of recumbent anthropometry, bioelectric impedance, and B-mode imaging ultrasound methods for estimating body composition and fat pattering that would be appropriate for epidemiologic studies. The underlying hypothesis of the study is that a combination of these methods can be used to estimate body composition and index fat patterning in the elderly in novel ways that circumvent factors, such as reduced mobility, that limit the application of conventional anthropometric and/or bioelectric impedance approaches. The first phase of the proposed research will involve the development and validation of methods for predicting body composition and fat pattern for a cross-sectional sample of 400 ambulatory, elderly men and women. The second phase will consist of the cross-validation of these methods using data from two independent samples.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG008510-01A1
Application #
3120173
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1990-08-15
Project End
1990-12-31
Budget Start
1990-08-15
Budget End
1990-12-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Wright State University
Department
Type
Schools of Medicine
DUNS #
City
Dayton
State
OH
Country
United States
Zip Code
45435
Baumgartner, R N; Ross, R; Heymsfield, S B (1998) Does adipose tissue influence bioelectric impedance in obese men and women? J Appl Physiol 84:257-62
Baumgartner, R N (1993) Body composition in elderly persons: a critical review of needs and methods. Prog Food Nutr Sci 17:223-60
Chumlea, W C; Guo, S S; Baumgartner, R N et al. (1993) Determination of body fluid compartments with multiple frequency bioelectric impedance. Basic Life Sci 60:23-6
Baumgartner, R N; Rhyne, R L; Garry, P J et al. (1993) Imaging techniques and anatomical body composition in aging. J Nutr 123:444-8
Chumlea, W C; Baumgartner, R N; Garry, P J et al. (1992) Fat distribution and blood lipids in a sample of healthy elderly people. Int J Obes Relat Metab Disord 16:125-33
Baumgartner, R N; Rhyne, R L; Troup, C et al. (1992) Appendicular skeletal muscle areas assessed by magnetic resonance imaging in older persons. J Gerontol 47:M67-72
Baumgartner, R N; Heymsfield, S B; Lichtman, S et al. (1991) Body composition in elderly people: effect of criterion estimates on predictive equations. Am J Clin Nutr 53:1345-53