Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG009822-02S1
Application #
3121742
Study Section
Immunobiology Study Section (IMB)
Project Start
1992-01-15
Project End
1995-12-31
Budget Start
1993-06-15
Budget End
1993-12-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Steed, Ashley L; Barton, Erik S; Tibbetts, Scott A et al. (2006) Gamma interferon blocks gammaherpesvirus reactivation from latency. J Virol 80:192-200
Barton, Erik S; Lutzke, Mary L; Rochford, Rosemary et al. (2005) Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency. J Virol 79:14149-60
Hale, Timothy J; Richardson, Bruce C; Sweet, Leonard I et al. (2002) Age-related changes in mature CD4+ T cells: cell cycle analysis. Cell Immunol 220:51-62
Lewandowski, G; Hobbs, M V (1998) Evidence for deficiencies in intracerebral cytokine production, adhesion molecule induction, and T cell recruitment in herpes simplex virus type-2 infected mice. J Neuroimmunol 81:58-65
Lewandowski, G; Hobbs, M; Geller, A (1998) Evidence that deficient IFN-gamma production is a biological basis of herpes simplex virus type-2 neurovirulence. J Neuroimmunol 81:66-75
Berking, C; Hobbs, M V; Chatelain, R et al. (1998) Strain-dependent cytokine profile and susceptibility to oleic acid anilide in a murine model of the toxic oil syndrome. Toxicol Appl Pharmacol 148:222-8
Nazaruk, R A; Rochford, R; Hobbs, M V et al. (1998) Functional diversity of the CD8(+) T-cell response to Epstein-Barr virus (EBV): implications for the pathogenesis of EBV-associated lymphoproliferative disorders. Blood 91:3875-83
Hobbs, M V; Ernst, D N (1997) T cell differentiation and cytokine expression in late life. Dev Comp Immunol 21:461-70
Franco, A; Guidotti, L G; Hobbs, M V et al. (1997) Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice. J Immunol 159:2001-8
Rochford, R; Cannon, M J; Sabbe, R E et al. (1997) Common and idiosyncratic patterns of cytokine gene expression by Epstein-Barr virus transformed human B cell lines. Viral Immunol 10:183-95

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