The Iowa 65+ Rural Health Study (RHS) began in 1982 with a baseline survey of 3673 persons 65 years of age and older, geographically-defined from two rural Iowa counties, under contract to the National Institute on Aging's Established Populations for Epidemiologic Study of the Elderly. The cohort subsequently underwent seven annual follow-up interviews, but since 1989 has been subject to passive surveillance only. While the RHS has been quite productive scientifically, contract funds do not allow further direct contact, and funds are being sought here for a ten-year in-person follow-up interview. This cohort now numbers over 2300 persons averaging 80 years of age with no loss to follow-up. This new interview would first offer substantial clinical and population information on physical, mental and social function in this age group from multiple observations over a ten year period, not otherwise generally available. More specifically, among the special studies that this encounter would allow in this age group are: a) repeat in-home physical performance testing and determination of the natural history and correlates of these measures as well as selfreported information, b) testing of several environmental and clinical hypotheses relating to the trajectory of selected tests of cognitive function and their functional correlates, c) the relation of blood lipid and lipoprotein levels to cardiovascular outcomes, and d) the continued assessment of autodriving patterns, determinants and risk factors for accidents.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG010127-02
Application #
2051358
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1992-05-20
Project End
1995-04-30
Budget Start
1993-05-01
Budget End
1995-04-30
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Iowa
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Clark, Cheryl R; Kawachi, Ichiro; Ryan, Louise et al. (2009) Perceived neighborhood safety and incident mobility disability among elders: the hazards of poverty. BMC Public Health 9:162
Bassuk, Shari S; Berkman, Lisa F; Amick 3rd, Benjamin C (2002) Socioeconomic status and mortality among the elderly: findings from four US communities. Am J Epidemiol 155:520-33
Cerhan, J R; Pavuk, M; Wallace, R B (1999) Positive association between resting pulse and cancer incidence in current and former smokers. Ann Epidemiol 9:34-44
Cerhan, J R; Chiu, B C; Wallace, R B et al. (1998) Physical activity, physical function, and the risk of breast cancer in a prospective study among elderly women. J Gerontol A Biol Sci Med Sci 53:M251-6
Cerhan, J R; Torner, J C; Lynch, C F et al. (1997) Association of smoking, body mass, and physical activity with risk of prostate cancer in the Iowa 65+ Rural Health Study (United States). Cancer Causes Control 8:229-38
Cerhan, J R; Wallace, R B (1997) Change in social ties and subsequent mortality in rural elders. Epidemiology 8:475-81
Chung, H; Roberts, C T; Greenberg, S et al. (1996) Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease. Ann Neurol 39:800-3
Hyman, B T; Gomez-Isla, T; Briggs, M et al. (1996) Apolipoprotein E and cognitive change in an elderly population. Ann Neurol 40:55-66
Guralnik, J M; Ferrucci, L; Simonsick, E M et al. (1995) Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 332:556-61