Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG010520-02
Application #
2051750
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Other Health Professions
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Kiaei, Mahmoud; Bush, Ashley I; Morrison, Brett M et al. (2004) Genetically decreased spinal cord copper concentration prolongs life in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci 24:7945-50
Nimchinsky, E A; Young, W G; Yeung, G et al. (2000) Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in G86R superoxide dismutase transgenic mice. J Comp Neurol 416:112-25
Lutz-Bucher, B; Gonzalez de Aguilar, J L; Rene, F et al. (1999) Oxidative stress and a murine superoxide dismutase-1 mutation promoting amyotrophic lateral sclerosis alter neurosecretion in the hypothalamo-neurohypophyseal axis. Neuroendocrinology 69:377-84
Gonzalez de Aguilar, J L; Gordon, J W; Rene, F et al. (1999) A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis. Eur J Neurosci 11:4179-87
Morrison, B M; Janssen, W G; Gordon, J W et al. (1998) Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice. J Comp Neurol 391:64-77
Morrison, B M; Morrison, J H; Gordon, J W (1998) Superoxide dismutase and neurofilament transgenic models of amyotrophic lateral sclerosis. J Exp Zool 282:32-47
Morrison, B M; Janssen, W G; Gordon, J W et al. (1998) Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice. J Comp Neurol 395:523-34
Morrison, B M; Gordon, J W; Ripps, M E et al. (1996) Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: neurochemical correlates of selective vulnerability. J Comp Neurol 373:619-31