Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG010598-13
Application #
2051819
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1991-09-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
13
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Guttridge, D C; Lau, A; Tran, L et al. (1997) Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. J Biol Chem 272:24117-20
Guttridge, D C; Cunningham, D D (1996) Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. J Neurochem 67:498-507
Donovan, F M; Vaughan, P J; Cunningham, D D (1994) Regulation of protease nexin-1 target protease specificity by collagen type IV. J Biol Chem 269:17199-205
Vaughan, P J; Cunningham, D D (1993) Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J Biol Chem 268:3720-7
Cunningham, D D; Pulliam, L; Vaughan, P J (1993) Protease nexin-1 and thrombin: injury-related processes in the brain. Thromb Haemost 70:168-71
Guttridge, D C; Lau, A L; Cunningham, D D (1993) Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts. J Biol Chem 268:18966-74