Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG010765-04
Application #
2051985
Study Section
Nutrition Study Section (NTN)
Program Officer
Finkelstein, David B
Project Start
1992-06-15
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Nutrition
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Zambell, Kirsten L; Fitch, Mark D; Fleming, Sharon E (2003) Acetate and butyrate are the major substrates for de novo lipogenesis in rat colonic epithelial cells. J Nutr 133:3509-15
Cremin Jr, John D; Fitch, Mark D; Fleming, Sharon E (2003) Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol 285:G105-14
Fitch, M D; Fleming, S E (1999) Metabolism of short-chain fatty acids by rat colonic mucosa in vivo. Am J Physiol 277:G31-40
Quan, J; Fitch, M D; Fleming, S E (1998) Rate at which glutamine enters TCA cycle influences carbon atom fate in intestinal epithelial cells. Am J Physiol 275:G1299-308
Cremin Jr, J D; Fleming, S E (1997) Glycolysis is a source of pyruvate for transamination of glutamine amino nitrogen in jejunal epithelial cells. Am J Physiol 272:G575-88
Fleming, S E; Gill, R (1997) Aging stimulates fatty acid oxidation in rat colonocytes but does not influence the response to dietary fiber. J Gerontol A Biol Sci Med Sci 52:B318-30
Kight, C E; Fleming, S E (1995) Oxidation of glucose carbon entering the TCA cycle is reduced by glutamine in small intestine epithelial cells. Am J Physiol 268:G879-88
Fleming, S E; Kight, C E (1994) The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells. Can J Physiol Pharmacol 72:266-74
Fleming, S E; Youngman, L D; Ames, B N (1994) Intestinal cell proliferation is influenced by intakes of protein and energy, aflatoxin, and whole-body radiation. Nutr Cancer 22:11-30
Fleming, S E; Fitch, M D; Hudes, M (1994) Intestinal cell respiration is influenced by animal age, strain, and feeding status. J Gerontol 49:B22-30