Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG010851-01A2
Application #
3122822
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1993-12-01
Project End
1994-07-31
Budget Start
1993-12-01
Budget End
1994-07-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Collier, Timothy J; Kanaan, Nicholas M; Kordower, Jeffrey H (2011) Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates. Nat Rev Neurosci 12:359-66
Pitzer, Mark R; Sortwell, Caryl E; Daley, Brian F et al. (2003) Angiogenic and neurotrophic effects of vascular endothelial growth factor (VEGF165): studies of grafted and cultured embryonic ventral mesencephalic cells. Exp Neurol 182:435-45
Collier, Timothy J; Steece-Collier, Kathy; McGuire, Susan et al. (2003) Cellular models to study dopaminergic injury responses. Ann N Y Acad Sci 991:140-51
Collier, Timothy J; Sortwell, Caryl E; Elsworth, John D et al. (2002) Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease. J Comp Neurol 442:320-30
Sortwell, C E; Camargo, M D; Pitzer, M R et al. (2001) Diminished survival of mesencephalic dopamine neurons grafted into aged hosts occurs during the immediate postgrafting interval. Exp Neurol 169:23-9
Sortwell, C E; Daley, B F; Pitzer, M R et al. (2000) Oligodendrocyte-type 2 astrocyte-derived trophic factors increase survival of developing dopamine neurons through the inhibition of apoptotic cell death. J Comp Neurol 426:143-53
Ling, Z D; Collier, T J; Sortwell, C E et al. (2000) Striatal trophic activity is reduced in the aged rat brain. Brain Res 856:301-9
Collier, T J; Sortwell, C E; Daley, B F (1999) Diminished viability, growth, and behavioral efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: an argument for neurotrophic supplementation. J Neurosci 19:5563-73
Collier, T J; Sortwell, C E (1999) Therapeutic potential of nerve growth factors in Parkinson's disease. Drugs Aging 14:261-87
Schauwecker, P E; Cogen, J P; Jiang, T et al. (1998) Differential regulation of astrocytic mRNAs in the rat striatum after lesions of the cortex or substantia nigra. Exp Neurol 149:87-96

Showing the most recent 10 out of 13 publications