Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG011472-03
Application #
2052655
Study Section
Metabolism Study Section (MET)
Program Officer
Finkelstein, David B
Project Start
1994-01-01
Project End
1997-12-31
Budget Start
1996-02-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of South Carolina at Columbia
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
111310249
City
Columbia
State
SC
Country
United States
Zip Code
29208
Pamplona, R; Portero-Otin, M; Riba, D et al. (2000) Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans. J Gerontol A Biol Sci Med Sci 55:B286-91
Lyons, T J; Li, W; Wojciechowski, B et al. (2000) Aminoguanidine and the effects of modified LDL on cultured retinal capillary cells. Invest Ophthalmol Vis Sci 41:1176-80
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Pamplona, R; Portero-Otin, M; Ruiz, C et al. (1999) Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins. Free Radic Biol Med 27:901-10
Jenkins, A J; Li, W; Moller, K et al. (1999) Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells. Curr Eye Res 19:137-45
Miyata, T; van Ypersele de Strihou, C; Kurokawa, K et al. (1999) Alterations in nonenzymatic biochemistry in uremia: origin and significance of ""carbonyl stress"" in long-term uremic complications. Kidney Int 55:389-99
Onorato, J M; Thorpe, S R; Baynes, J W (1998) Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease. Ann N Y Acad Sci 854:277-90
Miyata, T; Fu, M X; Kurokawa, K et al. (1998) Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia? Kidney Int 54:1290-5

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