The primary purpose of this study is to develop ways of empirically clustering types of nonlinear mental and physical health trajectories, using 30 years of data from the Normative Aging Study (NAS), and to describe both the types of patterns that exist and the frequency of their occurrence. In addition to looking at cohort differences in these trajectories, the NAS data will be used to see if they are a function of personality, socioeconomic factors, and health behavior habits.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG013006-02
Application #
2517015
Study Section
Human Development and Aging Subcommittee 3 (HUD)
Project Start
1996-09-15
Project End
1999-08-31
Budget Start
1997-09-01
Budget End
1999-08-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California Davis
Department
Other Health Professions
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Ji, John S; Power, Melinda C; Sparrow, David et al. (2015) Lead exposure and tremor among older men: the VA normative aging study. Environ Health Perspect 123:445-50
Bakulski, Kelly M; Park, Sung Kyun; Weisskopf, Marc G et al. (2014) Lead exposure, B vitamins, and plasma homocysteine in men 55 years of age and older: the VA normative aging study. Environ Health Perspect 122:1066-74
Aldwin, Carolyn M; Jeong, Yu-Jin; Igarashi, Heidi et al. (2014) Do hassles mediate between life events and mortality in older men? Longitudinal findings from the VA Normative Aging Study. Exp Gerontol 59:74-80
Ikeda, Ai; Schwartz, Joel; Peters, Junenette L et al. (2011) Optimism in relation to inflammation and endothelial dysfunction in older men: the VA Normative Aging Study. Psychosom Med 73:664-71
Kaye, Elizabeth Krall; Valencia, Aileen; Baba, Nivine et al. (2010) Tooth loss and periodontal disease predict poor cognitive function in older men. J Am Geriatr Soc 58:713-8
van de Rest, Ondine; Spiro 3rd, Avron; Krall-Kaye, Elizabeth et al. (2009) Intakes of (n-3) fatty acids and fatty fish are not associated with cognitive performance and 6-year cognitive change in men participating in the Veterans Affairs Normative Aging Study. J Nutr 139:2329-36
Rajan, Pradeep; Kelsey, Karl T; Schwartz, Joel D et al. (2008) Interaction of the delta-aminolevulinic acid dehydratase polymorphism and lead burden on cognitive function: the VA normative aging study. J Occup Environ Med 50:1053-61
Rajan, Pradeep; Kelsey, Karl T; Schwartz, Joel D et al. (2007) Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study. Am J Epidemiol 166:1400-8
Wang, Florence T; Hu, Howard; Schwartz, Joel et al. (2007) Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline. Environ Health Perspect 115:1210-5
Weisskopf, Marc G; Hu, Howard; Sparrow, David et al. (2007) Proton magnetic resonance spectroscopic evidence of glial effects of cumulative lead exposure in the adult human hippocampus. Environ Health Perspect 115:519-23

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