Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG013070-01A1
Application #
2054975
Study Section
Special Emphasis Panel (ZRG4-GRM (01))
Project Start
1996-02-01
Project End
2001-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Welle, Stephen (2002) Cellular and molecular basis of age-related sarcopenia. Can J Appl Physiol 27:19-41
Welle, Stephen; Bhatt, Kirti; Shah, Bharati et al. (2002) Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62-77 and 21-31 yr old men. Exp Gerontol 37:833-9
Welle, S; Brooks, A; Thornton, C A (2001) Senescence-related changes in gene expression in muscle: similarities and differences between mice and men. Physiol Genomics 5:67-73
Welle, S; Bhatt, K; Thornton, C A (2000) High-abundance mRNAs in human muscle: comparison between young and old. J Appl Physiol 89:297-304
Welle, S; Bhatt, K; Thornton, C A (1999) Inventory of high-abundance mRNAs in skeletal muscle of normal men. Genome Res 9:506-13
Welle, S; Bhatt, K; Thornton, C A (1999) Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA. J Appl Physiol 86:1220-5
Welle, S (1998) Growth hormone and insulin-like growth factor-I as anabolic agents. Curr Opin Clin Nutr Metab Care 1:257-62
Welle, S; Thornton, C A (1998) High-protein meals do not enhance myofibrillar synthesis after resistance exercise in 62- to 75-yr-old men and women. Am J Physiol 274:E677-83
Welle, S; Thornton, C; Bhatt, K et al. (1997) Expression of elongation factor-1 alpha and S1 in young and old human skeletal muscle. J Gerontol A Biol Sci Med Sci 52:B235-9
Welle, S; Thornton, C (1997) Insulin-like growth factor-I, actin, and myosin heavy chain messenger RNAs in skeletal muscle after an injection of growth hormone in subjects over 60 years old. J Endocrinol 155:93-7

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