Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG013617-02
Application #
2055621
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1995-08-15
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Ayala, Ramses; Kett, Lauren R; Leach, Tiffany L et al. (2012) Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. J Neurosci Methods 204:221-6
Benn, Caroline L; Luthi-Carter, Ruth; Kuhn, Alexandre et al. (2010) Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease. J Neuropathol Exp Neurol 69:817-27
Young, Anne B (2009) Four decades of neurodegenerative disease research: how far we have come! J Neurosci 29:12722-8
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Zucker, Birgit; Luthi-Carter, Ruth; Kama, Jibrin A et al. (2005) Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Hum Mol Genet 14:179-89
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Luthi-Carter, Ruth; Strand, Andrew D; Hanson, Sarah A et al. (2002) Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum Mol Genet 11:1927-37
Luthi-Carter, Ruth; Hanson, Sarah A; Strand, Andrew D et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 11:1911-26
Chan, Edmond Y W; Luthi-Carter, Ruth; Strand, Andrew et al. (2002) Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Hum Mol Genet 11:1939-51

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