;s Abstracts): Older adults experience a marked decline in muscle mass (sarcopenia) and strength that can have a significant effect on the activities of daily living. As a countermeasure, a number of groups have shown that these individuals can experience a substantial increase in strength after participation in short-duration, strength training programs. Although most of these programs have involved heavy-load protocols, the investigators recent observations suggest that comparable gains in strength can be achieved with light loads if the participant focuses on exerting a steady force during each exercise. The investigators propose to test the hypothesis that older adults can increase muscle strength and achieve functional benefits with a strength-training program based on the use of steady contractions to lift light loads.
The specific aims will be: (1) to compare the effects of training load on the changes in muscle strength; (2) to assess the functional consequences of the training-induced increase in muscle strength; and (3) to characterize the types of neural adaptations that underlie the increase in strength.
These aims will be examined by recruiting older adults (65-80 years) to participate in a 16-week strength-training program. The predictor variables will be muscle group (knee-extensor or hand-forearm muscles), training load (30 or 80% of maximum), and degree of control (regular or steady muscle contractions). The outcome variables will be muscle strength, performance on functional tests, and the adaptations underlying the increase in strength. The investigators expect to find that older adults will be able to increase muscle strength in a program that uses light training and steady muscle contractions and that such a program will have a greater transfer to functional activities. This finding will underscore the critical role of neural adaptations in the strength gains experienced by older adults with short-duration training and will provide the foundation for an alternative therapeutic strategy for strengthening exercises in this population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG013929-01A2
Application #
2472232
Study Section
Special Emphasis Panel (ZRG4-GRM (01))
Project Start
1997-12-01
Project End
2000-11-30
Budget Start
1997-12-01
Budget End
1998-11-30
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Colorado at Boulder
Department
Physiology
Type
Schools of Arts and Sciences
DUNS #
City
Boulder
State
CO
Country
United States
Zip Code
80309
Tracy, Brian L; Enoka, Roger M (2006) Steadiness training with light loads in the knee extensors of elderly adults. Med Sci Sports Exerc 38:735-45
Tracy, Brian L; Byrnes, William C; Enoka, Roger M (2004) Strength training reduces force fluctuations during anisometric contractions of the quadriceps femoris muscles in old adults. J Appl Physiol 96:1530-40
Enoka, Roger M; Christou, Evangelos A; Hunter, Sandra K et al. (2003) Mechanisms that contribute to differences in motor performance between young and old adults. J Electromyogr Kinesiol 13:1-12
Tracy, Brian L; Enoka, Roger M (2002) Older adults are less steady during submaximal isometric contractions with the knee extensor muscles. J Appl Physiol 92:1004-12
Noteboom, J T; Barnholt, K R; Enoka, R M (2001) Activation of the arousal response and impairment of performance increase with anxiety and stressor intensity. J Appl Physiol 91:2093-101
Enoka, R M; Fuglevand, A J (2001) Motor unit physiology: some unresolved issues. Muscle Nerve 24:4-17
Noteboom, J T; Fleshner, M; Enoka, R M (2001) Activation of the arousal response can impair performance on a simple motor task. J Appl Physiol 91:821-31