Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG020603-03
Application #
6787721
Study Section
Special Emphasis Panel (ZRG1-BDCN-3 (01))
Program Officer
Snyder, Stephen D
Project Start
2002-09-30
Project End
2007-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
3
Fiscal Year
2004
Total Cost
$308,750
Indirect Cost

  Institution

Name
Stanford University
Department
Neurology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305

  Publications

Tesseur, Ina; Nguyen, Andy; Chang, Betty et al. (2017) Deficiency in Neuronal TGF-? Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-? Signaling Protects against MPTP Neurotoxicity in Mice. J Neurosci 37:4584-4592
Luo, Jian; Elwood, Fiona; Britschgi, Markus et al. (2013) Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival. J Exp Med 210:157-72
Lucin, Kurt M; O'Brien, Caitlin E; Bieri, Gregor et al. (2013) Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron 79:873-86
Britschgi, Markus; Takeda-Uchimura, Yoshiko; Rockenstein, Edward et al. (2012) Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. J Neuroinflammation 9:220
Moriyama, Maiko; Fukuhara, Takeshi; Britschgi, Markus et al. (2011) Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis. J Neurosci 31:3981-9
Britschgi, M; Olin, C E; Johns, H T et al. (2009) Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc Natl Acad Sci U S A 106:12145-50
Luo, Jian; Wyss-Coray, Tony (2009) Bioluminescence analysis of Smad-dependent TGF-beta signaling in live mice. Methods Mol Biol 574:193-202
Pickford, Fiona; Masliah, Eliezer; Britschgi, Markus et al. (2008) The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 118:2190-9
Luo, Jian; Ho, Peggy; Steinman, Lawrence et al. (2008) Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease. J Neuroinflammation 5:6
Luo, Jian; Ho, Peggy P; Buckwalter, Marion S et al. (2007) Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. J Clin Invest 117:3306-15

Showing the most recent 10 out of 18 publications