Previous theory and research implicates participation in meaningful activity as an important factor in enhancing older adults' health-related quality of life. Consistent with this emphasis, a previous R01 grant completed by our study group demonstrated that an activity-based intervention (the Well Elderly Intervention) reduced declines in a wide variety of health-related parameters among low income, ethnically diverse elders. In the currently proposed four-year project, we aim to replicate our previous result while simultaneously examining the mediating mechanisms responsible for its positive effects. The outcomes of this study will provide important new information about the process events by which activity-based lifestyle interventions influence key aging outcomes. In the proposed study, 440 ethnically diverse elders recruited from a variety of sites in the urban Los Angeles area will participate in a randomized experiment containing a semi-crossover design component. Within either the first or second six-month phase of their study involvement, each subject will receive a lifestyle-based intervention designed to improve a variety of aging outcomes. At 4-5 points in time over an 18-24 month interval, elders will complete assessments of healthy activity, coping, social support, perceived control, stress-related biomarkers, perceived physical health, psychosocial well-being, and cognitive functioning to test the efficacy of the intervention and document the process mechanisms responsible for its effects. The study has three long-term objectives. First, it will lead to more effective health care services for our nation's rapidly growing elderly population, thereby fulfilling a major policy priority for older adults, namely, preventing declines in their health and independence. Second, it will generate new information regarding how activity influences aging outcomes. Although previous research has shown that activity patterns consistently relate to important aging outcomes, little is known about how the psychological and biological changes that stem from activities combine to promote successful aging. The proposed study will reduce this knowledge gap. Third, due to the significant ethnic diversity at the study sites, the project will produce results that generalize to minority elders. This outcome is important due to the increasing ethnic diversity of our nation's aging population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG021108-01A2
Application #
6727147
Study Section
Social Sciences, Nursing, Epidemiology and Methods 4 (SNEM)
Program Officer
Stahl, Sidney M
Project Start
2004-05-01
Project End
2008-04-30
Budget Start
2004-05-01
Budget End
2005-04-30
Support Year
1
Fiscal Year
2004
Total Cost
$605,860
Indirect Cost
Name
University of Southern California
Department
Other Health Professions
Type
Schools of Dentistry
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Juang, Christine; Knight, Bob G; Carlson, Mike et al. (2018) Understanding the Mechanisms of Change in a Lifestyle Intervention for Older Adults. Gerontologist 58:353-361
Leland, Natalie E; Fogelberg, Donald; Sleight, Alix et al. (2016) Napping and Nighttime Sleep: Findings From an Occupation-Based Intervention. Am J Occup Ther 70:7004270010p1-7
Wilcox, Rand R; Granger, Douglas A; Szanton, Sarah et al. (2014) Cortisol diurnal patterns, associations with depressive symptoms, and the impact of intervention in older adults: results using modern robust methods aimed at dealing with low power due to violations of standard assumptions. Horm Behav 65:219-25
Wilcox, Rand R; Granger, Douglas A; Szanton, Sarah et al. (2014) Diurnal patterns and associations among salivary cortisol, DHEA and alpha-amylase in older adults. Physiol Behav 129:11-6
Carlson, Mike; Jackson, Jeanne; Mandel, Deborah et al. (2014) Predictors of retention among African American and Hispanic older adult research participants in the Well Elderly 2 randomized controlled trial. J Appl Gerontol 33:357-82
Mallinson, Trudy; Schepens Niemiec, Stacey L; Carlson, Mike et al. (2014) Development and validation of the activity significance personal evaluation (ASPEn) scale. Aust Occup Ther J 61:384-93
Wilcox, Rand; Carlson, Mike; Azen, Stan et al. (2013) Avoid lost discoveries, because of violations of standard assumptions, by using modern robust statistical methods. J Clin Epidemiol 66:319-29
Wilcox, Rand R (2013) A HETEROSCEDASTIC METHOD FOR COMPARING REGRESSION LINES AT SPECIFIED DESIGN POINTS WHEN USING A ROBUST REGRESSION ESTIMATOR. J Data Sci 11:281-291
Clark, Florence; Jackson, Jeanne; Carlson, Mike et al. (2012) Effectiveness of a lifestyle intervention in promoting the well-being of independently living older people: results of the Well Elderly 2 Randomised Controlled Trial. J Epidemiol Community Health 66:782-90
Eakman, Aaron M (2012) Measurement characteristics of the engagement in meaningful activities survey in an age-diverse sample. Am J Occup Ther 66:e20-9

Showing the most recent 10 out of 16 publications