Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG021127-03
Application #
6787714
Study Section
Special Emphasis Panel (ZRG1-MDCN-2 (01))
Program Officer
Snyder, Stephen D
Project Start
2002-09-15
Project End
2007-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
3
Fiscal Year
2004
Total Cost
$360,050
Indirect Cost
Name
University of Washington
Department
Physiology
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
de Laat, Rian; Meabon, James S; Wiley, Jesse C et al. (2015) LINGO-1 promotes lysosomal degradation of amyloid-? protein precursor. Pathobiol Aging Age Relat Dis 5:25796
Wiley, Jesse C; Smith, Elise A; Hudson, Mark P et al. (2007) Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain. J Biol Chem 282:33313-25
Wiley, Jesse C; Hudson, Mark; Kanning, Kevin C et al. (2005) Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment. J Neurochem 94:1189-201