The long-term objective of this research is a prophylactic approach that can reduce the incidence of falls and the resulting injuries among older adults at risk and thus reduce its escalating medical cost. This project explores perturbation training through the use of treadmill device and a motor learning approach, in which experience with slip-like perturbation generated by that treadmill is used to prepare the motor system to develop and then put to use fall-resisting skills outside of training environment (cross-environment transfer). The computer-controlled treadmill is portable, safe and easy to operate, thus conducive for use in clinics or community centers. The study logically builds on and complements the team's previous and current research programs, and will further test that after such a single session, older adults at risk can retain such cross- environment transfer and reduce their likelihood of falls in everyday living for the next 6 to 12 months. Finally, the study will explore that such reduction of falls does not come merely from these persons'familiarity with the training or testing setup, protocol and environments.

Public Health Relevance

Falls among older adults, whether or not resulting in an injury, often lead to decreases in mobility and self- imposed limitations on independence, daily activities, and socialization. Injuries resulting from falls such as hip fractures, on the other had, affect a broad range of elderly persons, not only the frail or impaired, but also those who are vigorous and active. The proposed research addresses this major public health concern;given the projected increase in the size of this population, such preventive measure could make a significant contribution to managing our nation's healthcare costs and improving the quality of life for the elderly.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Project (R01)
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Study Section
Musculoskeletal Rehabilitation Sciences Study Section (MRS)
Program Officer
Joseph, Lyndon
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University of Illinois at Chicago
Other Health Professions
Sch Allied Health Professions
United States
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Lee, Anna; Bhatt, Tanvi; Smith-Ray, Renae L et al. (2018) Gait Speed and Dynamic Stability Decline Accelerates Only in Late Life: A Cross-sectional Study in Community-Dwelling Older Adults. J Geriatr Phys Ther :
Lee, Anna; Bhatt, Tanvi; Liu, Xuan et al. (2018) Can higher training practice dosage with treadmill slip-perturbation necessarily reduce risk of falls following overground slip? Gait Posture 61:387-392
Wang, Shuaijie; Liu, Xuan; Lee, Anna et al. (2017) Can Recovery Foot Placement Affect Older Adults' Slip-Fall Severity? Ann Biomed Eng 45:1941-1948
Liu, Xuan; Reschechtko, Sasha; Wang, Shuaijie et al. (2017) The recovery response to a novel unannounced laboratory-induced slip: The ""first trial effect"" in older adults. Clin Biomech (Bristol, Avon) 48:9-14
Liu, Xuan; Bhatt, Tanvi; Wang, Shuaijie et al. (2017) Retention of the ""first-trial effect"" in gait-slip among community-living older adults. Geroscience 39:93-102
Liu, Xuan; Bhatt, Tanvi; Pai, Yi-Chung Clive (2016) Intensity and generalization of treadmill slip training: High or low, progressive increase or decrease? J Biomech 49:135-40
Lee, Anna; Bhatt, Tanvi; Pai, Yi-Chung (2016) Generalization of treadmill perturbation to overground slip during gait: Effect of different perturbation distances on slip recovery. J Biomech 49:149-54