Role of T-Cells and Immunity to Cryptococcosis

Murphy, Juneann W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI015716-17
• Application #: 2060276
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1980-04-01
• Project End: 1998-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 17
• Fiscal Year: 1996

Institution

• Name: University of Oklahoma Health Sciences Center
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 937727907
• City: Oklahoma City
• State: OK
• Country: United States
• Zip Code: 73117

Publications

Jackson, Lydgia A; Drevets, Douglas A; Dong, Zhao-Ming et al. (2005) Levels of L-selectin (CD62L) on human leukocytes in disseminated cryptococcosis with and without associated HIV-1 infection. J Infect Dis 191:1361-7

Blackstock, Rebecca; Murphy, Juneann W (2004) Age-related resistance of C57BL/6 mice to Cryptococcus neoformans is dependent on maturation of NKT cells. Infect Immun 72:5175-80

Bauman, Sean K; Huffnagle, Gary B; Murphy, Juneann W (2003) Effects of tumor necrosis factor alpha on dendritic cell accumulation in lymph nodes draining the immunization site and the impact on the anticryptococcal cell-mediated immune response. Infect Immun 71:68-74

Nichols, Kasie L; Bauman, Sean K; Schafer, Fredda B et al. (2002) Differences in components at delayed-type hypersensitivity reaction sites in mice immunized with either a protective or a nonprotective immunogen of Cryptococcus neoformans. Infect Immun 70:591-600

Bauman, S K; Nichols, K L; Murphy, J W (2000) Dendritic cells in the induction of protective and nonprotective anticryptococcal cell-mediated immune responses. J Immunol 165:158-67

McGaha, T; Murphy, J W (2000) CTLA-4 down-regulates the protective anticryptococcal cell-mediated immune response. Infect Immun 68:4624-30

Blackstock, R; Buchanan, K L; Cherniak, R et al. (1999) Pathogenesis of Cryptococcus neoformans is associated with quantitative differences in multiple virulence factors. Mycopathologia 147:1-11

Doyle, H A; Murphy, J W (1999) Role of the C-C chemokine, TCA3, in the protective anticryptococcal cell-mediated immune response. J Immunol 162:4824-33

Blackstock, R; Buchanan, K L; Adesina, A M et al. (1999) Differential regulation of immune responses by highly and weakly virulent Cryptococcus neoformans isolates. Infect Immun 67:3601-9

Huffnagle, G B; McNeil, L K; McDonald, R A et al. (1999) Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. J Immunol 163:4642-6