The Viral Testing Core works closely with the Husbandry and Management Core to support the development and maintenance of the CNPRC SPF colony. The Core works collaboratively with the CNPRC Primate Assay Laboratory (PAL) to provide laboratory testing services, interpretation, troubleshooting and consultation to ensure that the colony remains free of the specified pathogens. The PAL has an excellent record designing and validating both in laboratory developed and commercial tests for these purposes. The PAL works with its counterpart laboratories throughout the NIH NPRC system to ensure that maximum accuracy standards are upheld. During the next grant period, the Viral Testing Core and PAL will work together to continue to evaluate and enhance existing testing protocols, reagents, and algorithms for maximum performance quality and efficiency. In addition, they will monitor emerging research discoveries and trends to provide testing for new animal models as warranted.

Project Start
2000-09-30
Project End
2024-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
21
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Yee, JoAnn L; Grant, Richard; Van Rompay, Koen K et al. (2017) Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies. J Med Primatol 46:149-153
Chang, W L William; Gonzalez, Denise F; Kieu, Hung T et al. (2017) Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques. PLoS One 12:e0170154
Yee, JoAnn L; Vanderford, Thomas H; Didier, Elizabeth S et al. (2016) Specific pathogen free macaque colonies: a review of principles and recent advances for viral testing and colony management. J Med Primatol 45:55-78
Oxford, Kristie L; Dela Pena-Ponce, Myra Grace A; Jensen, Kara et al. (2015) The interplay between immune maturation, age, chronic viral infection and environment. Immun Ageing 12:3
Yee, JoAnn L; Montiel, Nestor A; Ardeshir, Amir et al. (2013) Constitutive release of IFN? and IL2 from peripheral blood mononuclear cells of rhesus macaques (Macaca mulatta) infected with simian T-lymphotropic virus type 1. Comp Med 63:508-14