Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI018073-14
Application #
2060628
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1981-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
14
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Nataraj, C; Huffman, G R; Kurlander, R J (1998) H2M3wt-restricted, Listeria monocytogenes-immune CD8 T cells respond to multiple formylated peptides and to a variety of gram-positive and gram-negative bacteria. Int Immunol 10:7-15
Nataraj, C; Brown, M L; Poston, R M et al. (1996) H2-M3wt-restricted, Listeria monocytogenes-specific CD8 T cells recognize a novel, hydrophobic, protease-resistant, periodate-sensitive antigen. Int Immunol 8:367-78
Liu, W; Kurlander, R J (1995) Analysis of the interrelationship between IL-12, TNF-alpha, and IFN-gamma production during murine listeriosis. Cell Immunol 163:260-7
Poston, R M; Kurlander, R J (1992) Cytokine expression in vivo during murine listeriosis. Infection with live, virulent bacteria is required for monokine and lymphokine messenger RNA accumulation in the spleen. J Immunol 149:3040-4
Brown, M L; Fields, P E; Kurlander, R J (1992) Metabolic requirements for macrophage presentation of Listeria monocytogenes to immune CD8 cells. J Immunol 148:555-61
Kurlander, R J; Shawar, S M; Brown, M L et al. (1992) Specialized role for a murine class I-b MHC molecule in prokaryotic host defenses. Science 257:678-9
Poston, R M; Kurlander, R J (1991) Analysis of the time course of IFN-gamma mRNA and protein production during primary murine listeriosis. The immune phase of bacterial elimination is not temporally linked to IFN production in vivo. J Immunol 146:4333-7
Kurlander, R J; Hoffman, M; Kratz, S S et al. (1989) Comparison of the effects of IL-1 alpha and TNF-alpha on phagocyte accumulation and murine antibacterial immunity. Cell Immunol 123:9-22
Lukacs, K; Kurlander, R J (1989) MHC-unrestricted transfer of antilisterial immunity by freshly isolated immune CD8 spleen cells. J Immunol 143:3731-6
Lukacs, K; Kurlander, R (1989) Lyt-2+ T cell-mediated protection against listeriosis. Protection correlates with phagocyte depletion but not with IFN-gamma production. J Immunol 142:2879-86

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