Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI019032-08
Application #
3128453
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1983-04-01
Project End
1990-06-30
Budget Start
1990-04-01
Budget End
1990-06-30
Support Year
8
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92037
Hall, A L; Wilson, B S; Pfeiffer, J R et al. (1997) Relationship of ligand-receptor dynamics to actin polymerization in RBL-2H3 cells transfected with the human formyl peptide receptor. J Leukoc Biol 62:535-46
Domalewski, M D; Guyer, D A; Freer, R J et al. (1996) Fixation traps formyl peptide receptors in high and low affinity forms that can be regulated by GTP[S] in the absence of ligand. J Recept Signal Transduct Res 16:59-75
Nolan, J P; Posner, R G; Martin, J C et al. (1995) A rapid mix flow cytometer with subsecond kinetic resolution. Cytometry 21:223-9
Posner, R G; Fay, S P; Domalewski, M D et al. (1994) Continuous spectrofluorometric analysis of formyl peptide receptor ternary complex interactions. Mol Pharmacol 45:65-73
Fay, S P; Habbersett, R; Domalewski, M D et al. (1994) Multiparameter flow cytometric analysis of a pH sensitive formyl peptide with application to receptor structure and processing kinetics. Cytometry 15:148-53
Fay, S P; Domalewski, M D; Sklar, L A (1993) Evidence for protonation in the human neutrophil formyl peptide receptor binding pocket. Biochemistry 32:1627-31
Neubig, R R; Sklar, L A (1993) Subsecond modulation of formyl peptide-linked guanine nucleotide-binding proteins by guanosine 5'-O-(3-thio)triphosphate in permeabilized neutrophils. Mol Pharmacol 43:734-40
Mueller, H; Montoya, B; Sklar, L A (1992) Reversal of inhibitory pathways in neutrophils by protein kinase antagonists: a rational approach to the restoration of depressed cell function? J Leukoc Biol 52:400-6
Norgauer, J; Eberle, M; Fay, S P et al. (1991) Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils. J Immunol 146:975-80
Mueller, H; Weingarten, R; Ransnas, L A et al. (1991) Differential amplification of antagonistic receptor pathways in neutrophils. J Biol Chem 266:12939-43

Showing the most recent 10 out of 37 publications