Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI019494-14
Application #
3128840
Study Section
Experimental Virology Study Section (EVR)
Project Start
1982-04-01
Project End
1986-12-31
Budget Start
1986-01-01
Budget End
1986-12-31
Support Year
14
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Ivanova, L; Schlesinger, M J (1993) Site-directed mutations in the Sindbis virus E2 glycoprotein identify palmitoylation sites and affect virus budding. J Virol 67:2546-51
Harrison, S C; Strong, R K; Schlesinger, S et al. (1992) Crystallization of Sindbis virus and its nucleocapsid. J Mol Biol 226:277-80
Collier, N C; Knox, K; Schlesinger, M J (1991) Inhibition of influenza virus formation by a peptide that corresponds to sequences in the cytoplasmic domain of the hemagglutinin. Virology 183:769-72
Gaedigk-Nitschko, K; Schlesinger, M J (1991) Site-directed mutations in Sindbis virus E2 glycoprotein's cytoplasmic domain and the 6K protein lead to similar defects in virus assembly and budding. Virology 183:206-14
Gaedigk-Nitschko, K; Ding, M X; Levy, M A et al. (1990) Site-directed mutations in the Sindbis virus 6K protein reveal sites for fatty acylation and the underacylated protein affects virus release and virion structure. Virology 175:282-91
Gaedigk-Nitschko, K; Schlesinger, M J (1990) The Sindbis virus 6K protein can be detected in virions and is acylated with fatty acids. Virology 175:274-81
Ding, M X; Schlesinger, M J (1989) Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein. Virology 171:280-4
Wen, D; Ding, M X; Schlesinger, M J (1986) Expression of genes encoding vesicular stomatitis and Sindbis virus glycoproteins in yeast leads to formation of disulfide-linked oligomers. Virology 153:150-4
Wen, D Z; Schlesinger, M J (1986) Regulated expression of Sindbis and vesicular stomatitis virus glycoproteins in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 83:3639-43