Abstract

In order to provide a basis for controlling human babesiosis and Lyme disease in northeastern U.S., we shall determine whether the abundance of deer limits the abundance of the deer tick (Ixodes dammini), whether increased abundance of mice may inhibit transmission of babesiosis and whether the presence of squirrels or chipmunks inhibits transmission. The role of ants as predators of deer ticks will be evaluated. These experiments in quantitative epidemiology rest on a body of biological data recently obtained in the study location. Mathematical models will be used to evaluate and describe the results of these studies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI019693-03
Application #
3129075
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1983-01-01
Project End
1986-06-30
Budget Start
1985-01-01
Budget End
1986-06-30
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Type
Schools of Public Health
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code

  Publications

Goethert, Heidi K; Telford 3rd, Sam R (2014) Not ""out of Nantucket"": Babesia microti in southern New England comprises at least two major populations. Parasit Vectors 7:546
Krause, Peter J; Foley, Daniel T; Burke, Georgine S et al. (2006) Reinfection and relapse in early Lyme disease. Am J Trop Med Hyg 75:1090-4
Burke, Georgine; Wikel, Stephen K; Spielman, Andrew et al. (2005) Hypersensitivity to ticks and Lyme disease risk. Emerg Infect Dis 11:36-41
Krause, Peter J; McKay, Kathleen; Gadbaw, Joseph et al. (2003) Increasing health burden of human babesiosis in endemic sites. Am J Trop Med Hyg 68:431-6
Krause, Peter J; McKay, Kathleen; Thompson, Charles A et al. (2002) Disease-specific diagnosis of coinfecting tickborne zoonoses: babesiosis, human granulocytic ehrlichiosis, and Lyme disease. Clin Infect Dis 34:1184-91
Kiszewski, Anthony E; Spielman, Andrew (2002) Preprandial inhibition of re-mating in Ixodes ticks (Acari: Ixodidae). J Med Entomol 39:847-53
Telford 3rd, S R; Korenberg, E I; Goethert, H K et al. (2002) [Detection of natural foci of babesiosis and granulocytic ehrlichiosis in Russia] Zh Mikrobiol Epidemiol Immunobiol :21-5
Ebel, G D; Spielman, A; Telford 3rd, S R (2001) Phylogeny of North American Powassan virus. J Gen Virol 82:1657-65
Thompson, C; Spielman, A; Krause, P J (2001) Coinfecting deer-associated zoonoses: Lyme disease, babesiosis, and ehrlichiosis. Clin Infect Dis 33:676-85
Rich, S M; Armstrong, P M; Smith, R D et al. (2001) Lone star tick-infecting borreliae are most closely related to the agent of bovine borreliosis. J Clin Microbiol 39:494-7

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