Immune Response of Mosquitoes to Filarial Worms

Christensen, Bruce Martin

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI019769-07
• Application #: 3129169
• Study Section: Tropical Medicine and Parasitology Study Section (TMP)
• Project Start: 1983-04-01
• Project End: 1990-06-30
• Budget Start: 1989-07-01
• Budget End: 1990-06-30
• Support Year: 7
• Fiscal Year: 1989

Institution

• Name: University of Wisconsin Madison
• Type: Earth Sciences/Resources
• DUNS #: 161202122
• City: Madison
• State: WI
• Country: United States
• Zip Code: 53715

Publications

Choi, Young-Jun; Aliota, Matthew T; Mayhew, George F et al. (2014) Dual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm-mosquito interactions. PLoS Negl Trop Dis 8:e2905

Liu, Pingyang; Torrens-Spence, Michael P; Ding, Haizhen et al. (2013) Mechanism of cysteine-dependent inactivation of aspartate/glutamate/cysteine sulfinic acid ?-decarboxylases. Amino Acids 44:391-404

Choi, Young-Jun; Fuchs, Jeremy F; Mayhew, George F et al. (2012) Tissue-enriched expression profiles in Aedes aegypti identify hemocyte-specific transcriptome responses to infection. Insect Biochem Mol Biol 42:729-38

Liu, Pingyang; Ding, Haizhen; Christensen, Bruce M et al. (2012) Cysteine sulfinic acid decarboxylase activity of Aedes aegypti aspartate 1-decarboxylase: the structural basis of its substrate selectivity. Insect Biochem Mol Biol 42:396-403

Liu, Pingyang; Ge, Xiaomei; Ding, Haizhen et al. (2012) Role of glutamate decarboxylase-like protein 1 (GADL1) in taurine biosynthesis. J Biol Chem 287:40898-906

Han, Qian; Robinson, Howard; Ding, Haizhen et al. (2012) Evolution of insect arylalkylamine N-acetyltransferases: structural evidence from the yellow fever mosquito, Aedes aegypti. Proc Natl Acad Sci U S A 109:11669-74

Mehere, Prajwalini; Han, Qian; Christensen, Bruce M et al. (2011) Identification and characterization of two arylalkylamine N-acetyltransferases in the yellow fever mosquito, Aedes aegypti. Insect Biochem Mol Biol 41:707-14

Choi, Young-Jun; Ghedin, Elodie; Berriman, Matthew et al. (2011) A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi. PLoS Negl Trop Dis 5:e1409

Vavricka, Christopher; Han, Qian; Huang, Yongping et al. (2011) From L-dopa to dihydroxyphenylacetaldehyde: a toxic biochemical pathway plays a vital physiological function in insects. PLoS One 6:e16124

Aliota, Matthew T; Chen, Cheng-Chen; Dagoro, Henry et al. (2011) Filarial worms reduce Plasmodium infectivity in mosquitoes. PLoS Negl Trop Dis 5:e963