Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI021159-05S2
Application #
3131088
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1983-09-01
Project End
1991-05-31
Budget Start
1991-04-01
Budget End
1991-05-31
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Meharry Medical College
Department
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37208
Chaudhuri, Minu; Ott, Robert Daniel; Hill, George C (2006) Trypanosome alternative oxidase: from molecule to function. Trends Parasitol 22:484-91
Ott, Robert; Chibale, Kelly; Anderson, Sedrick et al. (2006) Novel inhibitors of the trypanosome alternative oxidase inhibit Trypanosoma brucei brucei growth and respiration. Acta Trop 100:172-84
Chaudhuri, Minu; Sharan, Rita; Hill, George C (2002) Trypanosome alternative oxidase is regulated post-transcriptionally at the level of RNA stability. J Eukaryot Microbiol 49:263-9
Ajayi, Wilfred U; Chaudhuri, Minu; Hill, George C (2002) Site-directed mutagenesis reveals the essentiality of the conserved residues in the putative diiron active site of the trypanosome alternative oxidase. J Biol Chem 277:8187-93
Chaudhuri, M; Ajayi, W; Hill, G C (1998) Biochemical and molecular properties of the Trypanosoma brucei alternative oxidase. Mol Biochem Parasitol 95:53-68
Chaudhuri, M; Hill, G C (1996) Cloning, sequencing, and functional activity of the Trypanosoma brucei brucei alternative oxidase. Mol Biochem Parasitol 83:125-9
Chaudhuri, M; Ajayi, W; Temple, S et al. (1995) Identification and partial purification of a stage-specific 33 kDa mitochondrial protein as the alternative oxidase of the Trypanosoma brucei brucei bloodstream trypomastigotes. J Eukaryot Microbiol 42:467-72
Wirtz, E; Sylvester, D; Hill, G C (1991) Characterization of a novel developmentally regulated gene from Trypanosoma brucei encoding a potential phosphoprotein. Mol Biochem Parasitol 47:119-28
Bass Jr, H S; Njogu, R M; Hill, G C (1990) Solubilization and partial purification of glycerol-3-phosphate oxidase from mitochondria of Trypanosoma brucei. Exp Parasitol 70:486-9
Le Febvre, R B; Hill, G C (1986) Trypanosoma rhodesiense: mitochondrial proteins of bloodstream and procyclic trypomastigotes. Exp Parasitol 62:85-91

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