Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI022510-01
Application #
3133659
Study Section
Virology Study Section (VR)
Project Start
1985-09-30
Project End
1988-08-31
Budget Start
1985-09-30
Budget End
1986-08-31
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Desai, S Y; Patel, R C; Sen, G C et al. (1995) Activation of interferon-inducible 2'-5' oligoadenylate synthetase by adenoviral VAI RNA. J Biol Chem 270:3454-61
Patel, R C; Stanton, P; McMillan, N M et al. (1995) The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. Proc Natl Acad Sci U S A 92:8283-7
Patel, R C; Stanton, P; Sen, G C (1994) Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin. J Biol Chem 269:18593-8
Wu, C; Ohmori, Y; Bandyopadhyay, S et al. (1994) Interferon-stimulated response element and NF kappa B sites cooperate to regulate double-stranded RNA-induced transcription of the IP-10 gene. J Interferon Res 14:357-63
Patel, R C; Sen, G C (1994) Characterization of the interactions between double-stranded RNA and the double-stranded RNA binding domain of the interferon induced protein kinase. Cell Mol Biol Res 40:671-82
Sen, G C; Ransohoff, R M (1993) Interferon-induced antiviral actions and their regulation. Adv Virus Res 42:57-102
Kalvakolanu, D V; Sen, G C (1993) Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-kappa B in mouse embryonal carcinoma cells. Proc Natl Acad Sci U S A 90:3167-71
Patel, R C; Sen, G C (1992) Construction and expression of an enzymatically active human-mouse chimeric double-stranded RNA-dependent protein kinase. J Interferon Res 12:389-93
Patel, R C; Sen, G C (1992) Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase. J Biol Chem 267:7671-6
Bandyopadhyay, S K; Sen, G C (1992) Role of protein phosphorylation in activation of interferon-stimulated gene factors. J Biol Chem 267:6389-95

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