Candida Acid Proteinase and Pathogenesis

Ray, Thomas L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI024344-06
• Application #: 2062557
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1988-02-01
• Project End: 1996-12-31
• Budget Start: 1995-01-01
• Budget End: 1996-12-31
• Support Year: 6
• Fiscal Year: 1995

Institution

• Name: University of Iowa
• Department: Dermatology
• Type: Schools of Medicine
• DUNS #: 041294109
• City: Iowa City
• State: IA
• Country: United States
• Zip Code: 52242

Publications

Abad-Zapatero, C; Goldman, R; Muchmore, S W et al. (1998) Structure of secreted aspartic proteinases from Candida. Implications for the design of antifungal agents. Adv Exp Med Biol 436:297-313

Abad-Zapatero, C; Goldman, R; Muchmore, S W et al. (1996) Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: implications for the design of antifungal agents. Protein Sci 5:640-52

Ray, T L; Payne, C D; Morrow, B J (1991) Candida albicans acid proteinase: characterization and role in candidiasis. Adv Exp Med Biol 306:173-83

Ray, T L; Payne, C D (1990) Comparative production and rapid purification of Candida acid proteinase from protein-supplemented cultures. Infect Immun 58:508-14