Hybridoma-Derived Human Suppressor Factors

Platsoucas, Chris D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI024669-03
• Application #: 3137822
• Study Section: Immunological Sciences Study Section (IMS)
• Project Start: 1988-12-01
• Project End: 1993-02-28
• Budget Start: 1990-12-01
• Budget End: 1993-02-28
• Support Year: 3
• Fiscal Year: 1991

Institution

• Name: University of Texas MD Anderson Cancer Center
• Type: Other Domestic Higher Education
• DUNS #: 001910777
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Fox, F E; Chernajovsky, Y; Platsoucas, C D (1994) Inhibition of interleukin 2 production and alteration of interleukin 2 mRNA processing by human T-T cell hybridoma-derived suppressor factors. Hybridoma 13:343-52

Fox, F E; Oleszak, E L; Chen, P F et al. (1992) Human hybridoma-derived suppressor factor 160 and transforming growth factor-beta are different molecules. Lymphokine Cytokine Res 11:307-15

Chen, P F; Platsoucas, C D (1992) Development of the non-palindromic adaptor polymerase chain reaction (NPA-PCR) for the amplification of alpha- and beta-chain T-cell receptor cDNAs. Scand J Immunol 35:539-49

Nanno, M; Seki, H; Ioannides, C G et al. (1992) Disulfide-linked and non-disulfide-linked gamma/delta T-cell antigen receptors: differential expression on T-cell lines and clones derived from normal donors and patients with primary immunodeficiency disorders. Anticancer Res 12:1069-78

Nanno, M; Seki, H; Mathioudakis, G et al. (1992) Gamma/delta T cell antigen receptors expressed on tumor-infiltrating lymphocytes from patients with solid tumors. Eur J Immunol 22:679-87

Kunicka, J E; Fox, F E; Seki, H et al. (1991) Hybridoma-derived human suppressor factors: inhibition of growth of tumor cell lines and effect on cytotoxic cells. Hum Antibodies Hybridomas 2:160-9

Morkowski, J J; Nanno, M; Chen, P F et al. (1991) IL-2-dependent murine T-cell lines and clones expressing gamma/delta T-cell antigen receptors. I. Functional and biochemical characterization. Scand J Immunol 34:779-94

Fox, F E; Platsoucas, C D (1990) Human T-T cell hybridomas: development and applications. Hum Antibodies Hybridomas 1:3-9

Ioannides, C G; Platsoucas, C D; Patenia, R et al. (1990) T-cell functions in ovarian cancer patients treated with viral oncolysates: I. Increased helper activity to immunoglobulins production. Anticancer Res 10:645-53

Ioannides, C G; Platsoucas, C D; Freedman, R S (1990) Immunological effects of tumor vaccines: II. T cell responses directed against cellular antigens in the viral oncolysates. In Vivo 4:17-24