Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI025224-06S1
Application #
3138621
Study Section
Experimental Virology Study Section (EVR)
Project Start
1989-07-01
Project End
1995-04-30
Budget Start
1992-07-01
Budget End
1993-04-30
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Meyer, B J; Southern, P J (1997) A novel type of defective viral genome suggests a unique strategy to establish and maintain persistent lymphocytic choriomeningitis virus infections. J Virol 71:6757-64
Zeller, J C; Nguyen, N; Southern, P J (1997) Differential immune recognition of LCMV nucleoprotein and glycoprotein in transgenic mice expressing LCMV cDNA genes. Virology 231:290-300
Butz, E A; Hostager, B S; Southern, P J (1994) Macrophages in mice acutely infected with lymphocytic choriomeningitis virus are primed for nitric oxide synthesis. Microb Pathog 16:283-95
Butz, E A; Southern, P J (1994) Lymphocytic choriomeningitis virus-induced immune dysfunction: induction of and recovery from T-cell anergy in acutely infected mice. J Virol 68:8477-80
Meyer, B J; Southern, P J (1994) Sequence heterogeneity in the termini of lymphocytic choriomeningitis virus genomic and antigenomic RNAs. J Virol 68:7659-64
Meyer, B J; Southern, P J (1993) Concurrent sequence analysis of 5' and 3' RNA termini by intramolecular circularization reveals 5' nontemplated bases and 3' terminal heterogeneity for lymphocytic choriomeningitis virus mRNAs. J Virol 67:2621-7
Southern, P J; Dyrberg, T; Schwimmbeck, P L et al. (1990) Persistent virus infection and development of virus-induced disease. J Autoimmun 3 Suppl 1:13-20
Fuller-Pace, F V; Southern, P J (1989) Detection of virus-specific RNA-dependent RNA polymerase activity in extracts from cells infected with lymphocytic choriomeningitis virus: in vitro synthesis of full-length viral RNA species. J Virol 63:1938-44
Francis, S J; Southern, P J (1988) Deleted viral RNAs and lymphocytic choriomeningitis virus persistence in vitro. J Gen Virol 69 ( Pt 8):1893-902