Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI025799-10
Application #
2063092
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1987-09-30
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Shiratsuchi, H; Ellner, J J (2001) Expression of IL-18 by Mycobacterium avium-infected human monocytes; association with M. avium virulence. Clin Exp Immunol 123:203-9
Shiratsuchi, H; Krukovets, I; Ellner, J J (2000) Role of T cell subsets in the modulation of Mycobacterium avium growth within human monocytes. Cell Immunol 202:12-Jun
Johnson, J L; Shiratsuchi, H; Toossi, Z et al. (1997) Altered IL-1 expression and compartmentalization in monocytes from patients with AIDS stimulated with Mycobacterium avium complex. J Clin Immunol 17:387-95
Shiratsuchi, H; Hamilton, B; Toossi, Z et al. (1996) Evidence against a role for interleukin-10 in the regulation of growth of Mycobacterium avium in human monocytes. J Infect Dis 173:410-7
Hirsch, C S; Ellner, J J; Russell, D G et al. (1994) Complement receptor-mediated uptake and tumor necrosis factor-alpha-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages. J Immunol 152:743-53
Shiratsuchi, H; Johnson, J L; Toossi, Z et al. (1994) Modulation of the effector function of human monocytes for Mycobacterium avium by human immunodeficiency virus-1 envelope glycoprotein gp120. J Clin Invest 93:885-91
Shiratsuchi, H; Toossi, Z; Mettler, M A et al. (1993) Colonial morphotype as a determinant of cytokine expression by human monocytes infected with Mycobacterium avium. J Immunol 150:2945-54
Mirando, W S; Shiratsuchi, H; Tubesing, K et al. (1992) Ultraviolet-irradiated monocytes efficiently inhibit the intracellular replication of Mycobacterium avium intracellulare. J Clin Invest 89:1282-7
Shiratsuchi, H; Johnson, J L; Ellner, J J (1991) Bidirectional effects of cytokines on the growth of Mycobacterium avium within human monocytes. J Immunol 146:3165-70
Johnson, J L; Shiratsuchi, H; Toba, H et al. (1991) Preservation of monocyte effector functions against Mycobacterium avium-M. intracellulare in patients with AIDS. Infect Immun 59:3639-45

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