Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI026067-01A1
Application #
3139665
Study Section
Immunobiology Study Section (IMB)
Project Start
1988-07-01
Project End
1990-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Dannecker, G; Mecheri, S; Hoffmann, M K (1992) In vivo presentation of Mls-1 antigen by T and B lymphocytes. Immunobiology 185:20-7
Dennig, D; Mecheri, S; Bourhis, J H et al. (1992) Interleukin-2 may enhance or inhibit antibody production by B cells depending on intracellular cAMP concentrations. Immunology 77:251-5
Mecheri, S; Dannecker, G; Dennig, D et al. (1991) B cells control the aggregability of CD4 on T cells through continuous physical interactions. Immunology 74:606-12
Dannecker, G; Mecheri, S; Hoffmann, M K (1991) Induction of neonatal tolerance to the Mls-1a self-super-antigen. Time kinetics and MHC restriction. J Immunol 147:2833-8
Dannecker, G; Mecheri, S; Staiano-Coico, L et al. (1991) A characteristic Mls-1a response precedes Mls-1a anergy in vivo. J Immunol 146:2083-7
Dennig, D; Mecheri, S; Dannecker, G et al. (1991) Does interleukin-1 save B cells from paralysis? Studies with pre-B cells and antigen-reactive B cells. Lymphokine Cytokine Res 10:27-34
Mecheri, S; Edidin, M; Dannecker, G et al. (1990) Immunogenic Ia-binding peptides immobilize the Ia molecule and facilitate its aggregation on the B cell membrane. Control by the M1s-1 gene. J Immunol 144:1361-8
Mecheri, S; Dannecker, G; Dennig, D et al. (1990) Immunogenic peptides require an undisturbed phospholipid cell membrane environment and must be amphipathic to immobilize Ia on B cells. J Immunol 144:1369-74