Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI026598-08
Application #
2063429
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

O'Grady, P; Krueger, N X; Streuli, M et al. (1994) Genomic organization of the human LAR protein tyrosine phosphatase gene and alternative splicing in the extracellular fibronectin type-III domains. J Biol Chem 269:25193-9
Pulido, R; Schlossman, S F; Saito, H et al. (1994) Identification of amino acids at the junction of exons 3 and 7 that are used for the generation of glycosylation-related human CD45RO and CD45RO-like antigen specificities. J Exp Med 179:1035-40
Furukawa, T; Itoh, M; Krueger, N X et al. (1994) Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain. Proc Natl Acad Sci U S A 91:10928-32
Saito, H; Streuli, M; Krueger, N X et al. (1992) CD45 and a family of receptor-linked protein tyrosine phosphatases. Biochem Soc Trans 20:165-9
Rothstein, D M; Saito, H; Streuli, M et al. (1992) The alternative splicing of the CD45 tyrosine phosphatase is controlled by negative regulatory trans-acting splicing factors. J Biol Chem 267:7139-47
Krueger, N X; Saito, H (1992) A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrases. Proc Natl Acad Sci U S A 89:7417-21
Itoh, M; Streuli, M; Krueger, N X et al. (1992) Purification and characterization of the catalytic domains of the human receptor-linked protein tyrosine phosphatases HPTP beta, leukocyte common antigen (LCA), and leukocyte common antigen-related molecule (LAR). J Biol Chem 267:12356-63
Streuli, M; Krueger, N X; Ariniello, P D et al. (1992) Expression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular region. EMBO J 11:897-907
Tsai, A Y; Itoh, M; Streuli, M et al. (1991) Isolation and characterization of temperature-sensitive and thermostable mutants of the human receptor-like protein tyrosine phosphatase LAR. J Biol Chem 266:10534-43
Saito, H; Streuli, M (1991) Molecular characterization of protein tyrosine phosphatases. Cell Growth Differ 2:59-65

Showing the most recent 10 out of 16 publications