Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI026918-08A1
Application #
2063631
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1988-07-01
Project End
2001-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Schneider, Christoph; O'Leary, Claire E; von Moltke, Jakob et al. (2018) A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling. Cell 174:271-284.e14
Miller, Corey N; Proekt, Irina; von Moltke, Jakob et al. (2018) Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature 559:627-631
Nusse, Ysbrand M; Savage, Adam K; Marangoni, Pauline et al. (2018) Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. Nature 559:109-113
Ricardo-Gonzalez, Roberto R; Van Dyken, Steven J; Schneider, Christoph et al. (2018) Tissue signals imprint ILC2 identity with anticipatory function. Nat Immunol 19:1093-1099
Nadjsombati, Marija S; McGinty, John W; Lyons-Cohen, Miranda R et al. (2018) Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit. Immunity 49:33-41.e7
Van Dyken, Steven J; Locksley, Richard M (2018) Chitins and chitinase activity in airway diseases. J Allergy Clin Immunol 142:364-369
Van Dyken, Steven J; Liang, Hong-Erh; Naikawadi, Ram P et al. (2017) Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease. Cell 169:497-509.e13
Savage, Adam K; Liang, Hong-Erh; Locksley, Richard M (2017) The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine. J Immunol 199:1912-1922
Singh, Priti B; Pua, Heather H; Happ, Hannah C et al. (2017) MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. J Exp Med 214:3627-3643
von Moltke, Jakob; O'Leary, Claire E; Barrett, Nora A et al. (2017) Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med 214:27-37

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