Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI026941-05S1
Application #
3141031
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1989-04-01
Project End
1994-03-31
Budget Start
1993-04-01
Budget End
1994-03-31
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Demaria, S; DeVito-Haynes, L D; Salter, R D et al. (1999) Peptide-conformed beta2m-free class I heavy chains are intermediates in generation of soluble HLA by the membrane-bound metalloproteinase. Hum Immunol 60:1216-26
Burlingham, W J; Jankowska-Gan, E; DeVito-Haynes, L et al. (1998) HLA (A*0201) mimicry by anti-idiotypic monoclonal antibodies. J Immunol 161:6705-14
DeVito-Haynes, L D; Demaria, S; Bushkin, Y et al. (1998) The metalloproteinase-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection. Hum Immunol 59:426-34
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DeVito, L D; Hogan, K T; Mason, B P et al. (1993) Epitope fine specificity of human anti-HLA-A2 antibodies. Transplant Proc 25:189-90
Niguma, T; DeVito, L D; Grailer, A P et al. (1993) HLA-A2-specific antibody production in severe combined immunodeficient mice reconstituted with human peripheral blood leukocytes from HLA-presensitized donors. Transplant Proc 25:239-40
De Vito, L D; Mason, B P; Jankowska-Gan, E et al. (1993) Epitope fine specificity of human anti-HLA-A2 antibodies. Identification of four epitopes including a haptenlike epitope on HLA-A2 at lysine 127. Hum Immunol 37:165-77

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