Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI027316-01
Application #
3141502
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1988-12-01
Project End
1993-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
School of Medicine & Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Drain, J; Bishop, J R; Hajduk, S L (2001) Haptoglobin-related protein mediates trypanosome lytic factor binding to trypanosomes. J Biol Chem 276:30254-60
Bishop, J R; Shimamura, M; Hajduk, S L (2001) Insight into the mechanism of trypanosome lytic factor-1 killing of Trypanosoma brucei brucei. Mol Biochem Parasitol 118:33-40
Moore, D R; Smith, A; Hager, K M et al. (1995) Developmentally regulated sensitivity of Trypanosoma brucei brucei to the cytotoxic effects of human high-density lipoprotein. Exp Parasitol 81:216-26
Tytler, E M; Moore, D R; Pierce, M A et al. (1995) Reconstitution of the trypanolytic factor from components of a subspecies of human high-density lipoproteins. Mol Biochem Parasitol 69:9-17
Hager, K M; Pierce, M A; Moore, D R et al. (1994) Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes. J Cell Biol 126:155-67
Hajduk, S L; Hager, K M; Esko, J D (1994) Human high density lipoprotein killing of African trypanosomes. Annu Rev Microbiol 48:139-62
Fultz, P N (1994) SIVsmmPBj14: an atypical lentivirus. Curr Top Microbiol Immunol 188:65-76