Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027849-02
Application #
3142122
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1989-06-01
Project End
1992-05-31
Budget Start
1990-06-01
Budget End
1991-05-31
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Adams, J C; Seed, B; Lu, N et al. (2009) Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress. Neuroscience 160:530-9
Medoff, Benjamin D; Seed, Brian; Jackobek, Ryan et al. (2006) CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma. J Immunol 176:7272-7
Xavier, Ramnik; Rabizadeh, Shahrooz; Ishiguro, Kazuhiro et al. (2004) Discs large (Dlg1) complexes in lymphocyte activation. J Cell Biol 166:173-8
Yang, Yi; Seed, Brian (2003) Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nat Biotechnol 21:447-51
Lichtenthaler, Stefan F; Dominguez, Diana-Ines; Westmeyer, Gil G et al. (2003) The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1. J Biol Chem 278:48713-9
Yang, Y; Kuang, Y; Montes De Oca, R et al. (2001) Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood 98:3435-40
Beck, P L; Xavier, R; Lu, N et al. (2000) Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology 119:699-705
Pimentel-Muinos, F X; Seed, B (1999) Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. Immunity 11:783-93
Fukumura, D; Xavier, R; Sugiura, T et al. (1998) Tumor induction of VEGF promoter activity in stromal cells. Cell 94:715-25
Xavier, R; Brennan, T; Li, Q et al. (1998) Membrane compartmentation is required for efficient T cell activation. Immunity 8:723-32

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